Corlanor and Northera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Corlanor (ivabradine hydrochloride) and Northera (droxidopa). Common drug interactions include drug intolerance among females and dysarthria among males.

The phase IV clinical study analyzes what interactions people have when they take Corlanor and Northera. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Corlanor?

Corlanor has active ingredients of ivabradine hydrochloride. eHealthMe is studying from 2,453 Corlanor users. Check the latest studies of Corlanor.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

On Jul, 14, 2026

62 people who take Corlanor and Northera together, and have interactions are studied.

Corlanor and Northera drug interactions.

What are the common drug interactions of Corlanor and Northera, by gender? *:

female:

Drug intolerance (drug sensitivity)
Dysphagia (a condition in which swallowing is difficult or painful)
Ear discomfort
Electrocardiogram qt prolonged
Eye irritation
Furuncle (infection of the hair follicle)
Genital rash (rash on sex organ)
Hot flush (sudden feelings of heat)
Hypokinesia (decreased bodily movement)
Infusion site bruising

male:

Dysarthria (speech disorder)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Presyncope
Swelling face
Dysphemia (stammering or stuttering)
Gait disturbance
Hypersensitivity

What are the common drug interactions of Corlanor and Northera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Heart rate decreased
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Headache (pain in head)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)

20-29:

Headache (pain in head)
Dizziness
Malaise (a feeling of general discomfort or uneasiness)
Vomiting
Pain
Pneumonia
Blood pressure decreased
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)
Dehydration (dryness resulting from the removal of water)

30-39:

Renal disorder (kidney disease)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Wound infection
Dizziness
Fatigue (feeling of tiredness)
Abdominal distension
Dyspnoea (difficult or laboured respiration)
Nasopharyngitis (inflammation of the nasopharynx)

40-49:

Dysstasia (difficulty in standing)
Loss of consciousness
Syncope (loss of consciousness with an inability to maintain postural tone)
Headache (pain in head)
Blood potassium decreased
Blood pressure increased
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Heart rate increased
Nausea (feeling of having an urge to vomit)

50-59:

Headache (pain in head)
Asthenia (weakness)
Blood pressure increased
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Palpitations (feelings or sensations that your heart is pounding or racing)
Swelling face
Blood pressure decreased
Bone pain
Chills (felling of cold)

60+:

Blood pressure increased
Dizziness
Headache (pain in head)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Fall
Death
Ear pain
Tinnitus (a ringing in the ears)
Viral infection

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 30 people, 48.39%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 15 people, 24.19%
Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 10 people, 16.13%
Fainting (loss of consciousness and postural tone): 4 people, 6.45%
Dizziness: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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