Cortef and Probiotics drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cortef (hydrocortisone) and Probiotics (yogurt). Common drug interactions include fatigue among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Cortef and Probiotics. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Cortef?

Cortef has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 4,254 Cortef users. Check the latest studies of Cortef.

What is Probiotics?

Probiotics has active ingredients of yogurt. It is often used in irritable bowel syndrome. eHealthMe is studying from 9,541 Probiotics users. Check the latest studies of Probiotics.

On Jul, 27, 2026

33 people who take Cortef and Probiotics together, and have interactions are studied.

Cortef and Probiotics drug interactions.

What are the common drug interactions of Cortef and Probiotics, by gender? *:

female:

Fatigue (feeling of tiredness)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Fall
Respiratory tract infection
Urinary tract infection
Pain
Sinusitis (inflammation of sinus)
Cellulitis (infection under the skin)
Weight increased

male:

Headache (pain in head)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Insulin-like growth factor increased
Low density lipoprotein increased (cholesterol increased in blood)
Lymphocyte count decreased
Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pain in extremity

What are the common drug interactions of Cortef and Probiotics, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal discomfort
Abdominal distension
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrointestinal pain
Overdose

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pain in extremity
Respiratory tract infection
Sinus disorder (disease of sinus)
Urinary tract infection
Localised infection (infection at the single location)
Oral infection
Sinusitis (inflammation of sinus)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cellulitis (infection under the skin)

50-59:

Arthralgia (joint pain)
Blood triglycerides increased
Cardiac murmur (an heart sound in valve abnormality)
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Insulin-like growth factor increased
Low density lipoprotein increased (cholesterol increased in blood)
Lymphocyte count decreased
Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
Myalgia (muscle pain)

60+:

Headache (pain in head)
Fall
Cellulitis (infection under the skin)
Cough
Dehydration (dryness resulting from the removal of water)
Gastrointestinal infection (infection of stomach and intestine)
Infection
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Malaise (a feeling of general discomfort or uneasiness)
Muscle strain (an injury to a muscle in which the muscle fibres tear)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 21 people, 63.64%
Renal Cell Carcinoma (a kidney cancer): 3 people, 9.09%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 9.09%
Migraine (headache): 2 people, 6.06%
Immune System Disorder: 2 people, 6.06%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 6.06%
Growth Hormone Deficiency: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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