Cortifoam and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cortifoam (hydrocortisone acetate) and Buscopan (hyoscine butylbromide). Common drug interactions include swelling among females.

The phase IV clinical study analyzes what interactions people have when they take Cortifoam and Buscopan. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Cortifoam?

Cortifoam has active ingredients of hydrocortisone acetate. eHealthMe is studying from 1,758 Cortifoam users. Check the latest studies of Cortifoam.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

43 people who take Cortifoam and Buscopan together, and have interactions are studied.

Cortifoam and Buscopan drug interactions.

What are the common drug interactions of Cortifoam and Buscopan, by gender? *:

female:

  1. Swelling
  2. Joint swelling
  3. Abdominal distension
  4. Abdominal pain
  5. Abnormal faeces (abnormal stool)
  6. Acne (skin problems that cause pimples)
  7. Anal fungal infection
  8. Asthenia (weakness)
  9. Back pain
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

male:

n/a

What are the common drug interactions of Cortifoam and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Joint swelling
  2. Pain
  3. Purulent discharge (discharge that contains pus)
  4. Rash
  5. Skin warm
  6. Subcutaneous abscess
  7. Swelling
  8. Abdominal pain upper
  9. Drug ineffective
  10. Erythema (redness of the skin)

40-49:

n/a

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Abdominal distension
  3. Diarrhoea
  4. Dysgeusia (disorder of the sense of taste)
  5. Dyspepsia (indigestion)
  6. Eye infection fungal
  7. Fatigue (feeling of tiredness)
  8. Flatulence (flatus expelled through the anus)
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Gastrointestinal pain

60+:

n/a

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 41 people, 95.35%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 37 people, 86.05%
  3. Abdominal Pain Upper: 30 people, 69.77%
  4. Abdominal Pain: 10 people, 23.26%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 16.28%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 16.28%
  7. Pain: 4 people, 9.30%
  8. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 9.30%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cortifoam and Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cortifoam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cortifoam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buscopan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate and hyoscine butylbromide (the active ingredients of Cortifoam and Buscopan, respectively), and Cortifoam and Buscopan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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