Cosentyx and Maxalt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosentyx (secukinumab) and Maxalt (rizatriptan benzoate). Common drug interactions include arthralgia among females and bulbar palsy among males.

The phase IV clinical study analyzes what interactions people have when they take Cosentyx and Maxalt. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.



On Jul, 10, 2026

49 people who take Cosentyx and Maxalt together, and have interactions are studied.

Cosentyx and Maxalt drug interactions.

What are the common drug interactions of Cosentyx and Maxalt, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Pain
  3. Skin disorder (skin disease)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Hot flush (sudden feelings of heat)
  6. Inflammation
  7. Rash morbilliform (a rash that looks like measles)
  8. Rash pruritic (redness with itching)
  9. Rectal haemorrhage (bleeding from anus)
  10. Skin infection

male:

  1. Bulbar palsy
  2. Deafness
  3. Upper respiratory tract inflammation
  4. Weight decreased
  5. Dyspepsia (indigestion)
  6. Headache (pain in head)
  7. Arthralgia (joint pain)
  8. Diarrhoea
  9. Fungal infection
  10. Iritis (painful inflammation of the iris of the eye)

What are the common drug interactions of Cosentyx and Maxalt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Arthralgia (joint pain)
  2. Ear infection staphylococcal (ear infection by staphylococcal bacteria)
  3. Pain
  4. Pruritus (severe itching of the skin)
  5. Rash
  6. Therapeutic response decreased (less preventive response)

20-29:

n/a

30-39:

  1. Influenza
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Diarrhoea
  5. Fungal infection
  6. Iritis (painful inflammation of the iris of the eye)
  7. Oral pain
  8. Pain
  9. Pruritus (severe itching of the skin)
  10. Pulmonary oedema (fluid accumulation in the lungs)

40-49:

  1. Drug ineffective
  2. Hypersensitivity
  3. Psoriasis (immune-mediated disease that affects the skin)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

  1. Pain
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Rash morbilliform (a rash that looks like measles)
  4. Rash pruritic (redness with itching)
  5. Rectal haemorrhage (bleeding from anus)
  6. Skin disorder (skin disease)
  7. Skin infection
  8. Skin ulcer
  9. Thermal burn (burn by heat)
  10. Injection site bruising

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Arthralgia (joint pain)
  3. Dyspepsia (indigestion)
  4. Headache (pain in head)
  5. Pruritus (severe itching of the skin)
  6. Skin burning sensation
  7. Stent placement

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 23 people, 46.94%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 24.49%
  3. Immunodeficiency Common Variable: 9 people, 18.37%
  4. Pain: 4 people, 8.16%
  5. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 6.12%
  6. Irritable Bowel Syndrome: 3 people, 6.12%
  7. Cardiac Disorder: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Cosentyx and Maxalt?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cosentyx and Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cosentyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosentyx and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on secukinumab and rizatriptan benzoate (the active ingredients of Cosentyx and Maxalt, respectively), and Cosentyx and Maxalt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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