Cosentyx and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosentyx (secukinumab) and Sumatriptan (sumatriptan succinate). Common drug interactions include skin plaque among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Cosentyx and Sumatriptan. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

51 people who take Cosentyx and Sumatriptan together, and have interactions are studied.

Cosentyx and Sumatriptan drug interactions.

What are the common drug interactions of Cosentyx and Sumatriptan, by gender? *:

female:

Skin plaque (red, scaly patches to appear on the skin)
Chest discomfort
Chest pain
Eye irritation
Infusion site erythema (reddening of the skin at infusion site)
Infusion site induration
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema peripheral (superficial swelling)
Pain in extremity
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Asthenia (weakness)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cluster headache (one-sided head pain with tearing)
Colitis (inflammation of colon)
Device occlusion
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Enteritis (inflammation of the small intestine)

What are the common drug interactions of Cosentyx and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sunburn

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Diarrhoea
Weight decreased

40-49:

Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arthralgia (joint pain)
Asthenia (weakness)
Infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Poor peripheral circulation
Sacral pain (pain at sacrum bone region)
Thrombosis (formation of a blood clot inside a blood vessel)
Weight decreased

50-59:

Abdominal pain
Lymphadenopathy (disease or enlargement of lymph nodes)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Neck pain
Pruritus (severe itching of the skin)
Uterine cyst
Uterine haemorrhage (uterine bleeding)
Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
Vaginal haemorrhage (vaginal bleeding)
Abdominal pain upper

60+:

n/a

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 25 people, 49.02%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 29.41%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 7.84%
Immune System Disorder: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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