Cosopt and Fml drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosopt (dorzolamide hydrochloride; timolol maleate) and Fml (fluorometholone). Common drug interactions include diarrhoea among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Cosopt and Fml. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Fml?

Fml has active ingredients of fluorometholone. eHealthMe is studying from 673 Fml users. Check the latest studies of Fml.

On Aug, 06, 2026

12 people who take Cosopt and Fml together, and have interactions are studied.

What are the common drug interactions of Cosopt and Fml, by gender? *:

female:

Diarrhoea
Visual impairment
Dry eye (lack of adequate tears)
Eye pain
Eye pruritus (eye itching)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Back pain
Cardiac arrest
Cardiac failure
Choking (mechanical obstruction of the flow of air from the environment into the lungs)

male:

Headache (pain in head)
Calculus bladder (bladder stone)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Photophobia (extreme sensitivity to light)
Upper respiratory tract infection
Vision blurred
Visual acuity reduced (reduced clearness of vision)
Weight decreased
Colon cancer
Drug ineffective

What are the common drug interactions of Cosopt and Fml, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Corneal erosion (failure of the cornea's outermost layer of epithelial cells to attach to the underlying)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Uveitis (inflammation of the uvea)
Visual impairment

50-59:

n/a

60+:

Diarrhoea
Drug ineffective
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypertension (high blood pressure)
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
Lacrimation increased
Leukopenia (less number of white blood cells in blood)
Ligament sprain (ligament stretched)

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 25.00%
Corneal Erosion (failure of the cornea's outermost layer of epithelial cells to attach to the underlying): 2 people, 16.67%
Uveitis (inflammation of the uvea): 1 person, 8.33%
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Gastritis (inflammation of stomach): 1 person, 8.33%
Diabetes: 1 person, 8.33%
Constipation: 1 person, 8.33%
Cataract (clouding of the lens inside the eye): 1 person, 8.33%
Herpes Simplex (herpes simplex is a common viral infection): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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