Cosopt and Oxaliplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosopt (dorzolamide hydrochloride; timolol maleate) and Oxaliplatin (oxaliplatin). Common drug interactions include diarrhoea among females and cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Cosopt and Oxaliplatin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Oxaliplatin?

Oxaliplatin has active ingredients of oxaliplatin. It is often used in colon cancer. eHealthMe is studying from 72,058 Oxaliplatin users. Check the latest studies of Oxaliplatin.

On Jul, 11, 2026

19 people who take Cosopt and Oxaliplatin together, and have interactions are studied.

Cosopt and Oxaliplatin drug interactions.

What are the common drug interactions of Cosopt and Oxaliplatin, by gender? *:

female:

Diarrhoea
Sudden death
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Hot flush (sudden feelings of heat)
Leukocytosis (increased white blood cells)
Mucosal inflammation (infection of mucous membrane)
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
Thrombocytopenia (decrease of platelets in blood)

male:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hepatic failure (liver failure)
Gastric cancer stage iv (cancer cells have spread to distant organs)
Metastatic gastric cancer (cancer types can spread to the stomach from other place)
Hyperglycaemia (high blood sugar)
Metastases to lymph nodes (cancer spreads to lymph node)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus inadequate control
Gastric cancer (stomach cancer)

What are the common drug interactions of Cosopt and Oxaliplatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hepatic failure (liver failure)
Metastatic gastric cancer (cancer types can spread to the stomach from other place)
Metastases to lymph nodes (cancer spreads to lymph node)
Gastric cancer (stomach cancer)
Gastric cancer stage ii (the tumour has penetrated the outer layer of the stomach. cancer cells have not spread to lymph nodes or other organs)
Gastric cancer stage iv (cancer cells have spread to distant organs)

60+:

Diarrhoea
Sudden death
Chills (felling of cold)
Cough
Death
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Infection
Malignant neoplasm progression (cancer tumour came back)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 10.53%
Pancreatic Insufficiency: 2 people, 10.53%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 10.53%
Oedema (fluid collection in tissue): 2 people, 10.53%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 10.53%
Intracardiac Thrombus (presence of a circumscribed mass with heart wall): 2 people, 10.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.53%
High Blood Pressure: 2 people, 10.53%
Diabetes: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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