Cosopt and Tafluprost drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosopt (dorzolamide hydrochloride; timolol maleate) and Tafluprost (tafluprost). Common drug interactions include insomnia among females and flatulence among males.

The phase IV clinical study analyzes what interactions people have when they take Cosopt and Tafluprost. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Tafluprost?

Tafluprost has active ingredients of tafluprost. eHealthMe is studying from 459 Tafluprost users. Check the latest studies of Tafluprost.

On Jul, 20, 2026

34 people who take Cosopt and Tafluprost together, and have interactions are studied.

Cosopt and Tafluprost drug interactions.

What are the common drug interactions of Cosopt and Tafluprost, by gender? *:

female:

Insomnia (sleeplessness)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Blindness unilateral
Bradycardia (abnormally slow heart action)
C-reactive protein increased
Diarrhoea
Diplopia (double vision)
Dyspnoea (difficult or laboured respiration)

male:

Flatulence (flatus expelled through the anus)
Prostatic specific antigen increased
Monoplegia (a paralysis of a single limb)
Myositis (inflammation of the muscles)
Vomiting
Drug ineffective
Abdominal distension
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cataract (clouding of the lens inside the eye)

What are the common drug interactions of Cosopt and Tafluprost, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Blindness unilateral
Bradycardia (abnormally slow heart action)
C-reactive protein increased
Diplopia (double vision)
Endocrine ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism)
Fatigue (feeling of tiredness)
Feeling hot
Fungal infection
Headache (pain in head)

40-49:

Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Lactic acidosis (low ph in body tissues)
Oropharyngeal discomfort (pain or irritation of oropharynx)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Abdominal pain
Constipation
Flatulence (flatus expelled through the anus)
Hallucination (an experience involving the perception of something not present)
Impaired gastric emptying
Vomiting
Alopecia (absence of hair from areas of the body)
Back pain
Blood glucose decreased
Eye disorder

60+:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Injection site cellulitis (injection site inflammation)
Monoplegia (a paralysis of a single limb)
Myositis (inflammation of the muscles)
Prostatic specific antigen increased
Drug ineffective
Visual impairment
Abdominal distension

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 14.71%
Stress And Anxiety: 3 people, 8.82%
Stable Angina (a constant chest pain): 3 people, 8.82%
Platelet Count Increased: 3 people, 8.82%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 8.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.82%
Pain: 2 people, 5.88%
Lower Urinary Tract Symptoms: 2 people, 5.88%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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