Cotazym and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cotazym (pancrelipase (amylase;lipase;protease)) and Humalog (insulin lispro recombinant). Common drug interactions include blood pressure decreased among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Cotazym and Humalog. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cotazym?

Cotazym has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 377 Cotazym users. Check the latest studies of Cotazym.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.



On Jul, 16, 2026

14 people who take Cotazym and Humalog together, and have interactions are studied.

Cotazym and Humalog drug interactions.

What are the common drug interactions of Cotazym and Humalog, by gender? *:

female:

  1. Blood pressure decreased
  2. Bronchopulmonary aspergillosis allergic (allergic lung disorder caused by aspergillus fungi)
  3. Cough
  4. Dyspnoea (difficult or laboured respiration)
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Forced expiratory volume decreased (decreased lung expired air volume)
  7. Lung disorder (lung disease)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  10. Productive cough

male:

  1. Death
  2. Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
  3. Cellulitis (infection under the skin)
  4. Drug hypersensitivity

What are the common drug interactions of Cotazym and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Asthenia (weakness)
  2. Chest discomfort
  3. Cystic fibrosis (disease of the secretary glands)
  4. Dyspnoea (difficult or laboured respiration)
  5. Forced expiratory volume decreased (decreased lung expired air volume)
  6. Lung disorder (lung disease)
  7. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)

30-39:

  1. Heart rate increased
  2. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  3. Lower respiratory tract infection
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Neuralgia (pain in one or more nerves)
  6. Weight decreased
  7. Blood pressure increased
  8. Fatigue (feeling of tiredness)
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Headache (pain in head)

40-49:

  1. Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
  2. Cellulitis (infection under the skin)
  3. Death

50-59:

n/a

60+:

  1. Death
  2. Drug hypersensitivity
  3. Drug ineffective

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 4 people, 28.57%
  2. Asthma: 4 people, 28.57%
  3. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 14.29%
  4. Osteoporosis (bones weak and more likely to break): 2 people, 14.29%
  5. Indigestion: 1 person, 7.14%
  6. High Blood Pressure: 1 person, 7.14%
  7. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cotazym and Humalog?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cotazym and Humalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotazym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Humalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cotazym and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Humalog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and insulin lispro recombinant (the active ingredients of Cotazym and Humalog, respectively), and Cotazym and Humalog (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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