Cotrim and Kalydeco drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cotrim (sulfamethoxazole; trimethoprim) and Kalydeco (ivacaftor). Common drug interactions include heart rate increased among females.
The phase IV clinical study analyzes what interactions people have when they take Cotrim and Kalydeco. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Cotrim?
Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.
What is Kalydeco?
Kalydeco has active ingredients of ivacaftor. eHealthMe is studying from 6,652 Kalydeco users. Check the latest studies of Kalydeco.
11 people who take Cotrim and Kalydeco together, and have interactions are studied.
What are the common drug interactions of Cotrim and Kalydeco, by gender? *:
female:
- Heart rate increased
- Bronchial secretion retention
- Dyspnoea (difficult or laboured respiration)
- Pyrexia (fever)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Pulmonary haemorrhage (acute bleeding from the lung)
- Oxygen saturation decreased
- Respiratory tract haemorrhage (respiratory tract bleeding)
- Sputum increased
male:
n/a
What are the common drug interactions of Cotrim and Kalydeco, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pulmonary haemorrhage (acute bleeding from the lung)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
30-39:
- Bronchial secretion retention
- Heart rate increased
- Oxygen saturation decreased
- Respiratory tract haemorrhage (respiratory tract bleeding)
- Secretion discharge
- Sputum increased
- Blood glucose decreased
- Frequent bowel movements
- Abscess rupture (pus release from the point of abscess)
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Cystic Fibrosis (disease of the secretary glands): 11 people, 100.00%
- C-Reactive Protein Increased: 8 people, 72.73%
- Nausea (feeling of having an urge to vomit): 1 person, 9.09%
- Headache (pain in head): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Cotrim and Kalydeco?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cotrim and Kalydeco:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cotrim:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Kalydeco:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cotrim and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kalydeco and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and ivacaftor (the active ingredients of Cotrim and Kalydeco, respectively), and Cotrim and Kalydeco (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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