Cotrim and Methylprednisolone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cotrim (sulfamethoxazole; trimethoprim) and Methylprednisolone acetate (methylprednisolone acetate). Common drug interactions include urinary tract infection among females and arthritis bacterial among males.

The phase IV clinical study analyzes what interactions people have when they take Cotrim and Methylprednisolone acetate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Methylprednisolone acetate?

Methylprednisolone acetate has active ingredients of methylprednisolone acetate. eHealthMe is studying from 2,816 Methylprednisolone acetate users. Check the latest studies of Methylprednisolone acetate.

On Jul, 05, 2026

13 people who take Cotrim and Methylprednisolone acetate together, and have interactions are studied.

Cotrim and Methylprednisolone acetate drug interactions.

What are the common drug interactions of Cotrim and Methylprednisolone Acetate, by gender? *:

female:

Urinary tract infection
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal discomfort
Abdominal pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Nausea (feeling of having an urge to vomit)
Pain
Procedural nausea

male:

Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Heat illness
Liver injury
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Osteomyelitis fungal (infection of bone by fungus)
Pain
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Swelling

What are the common drug interactions of Cotrim and Methylprednisolone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Gallbladder disorder
Abdominal discomfort
Abdominal pain
Nausea (feeling of having an urge to vomit)
Procedural nausea
Procedural vomiting
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Heat illness
Liver injury
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)

30-39:

Gallbladder disorder
Pain
Cholesterosis (abnormal deposition of cholesterol in tissues)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

40-49:

Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Urinary tract infection

50-59:

Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood creatinine increased
Hyperkalaemia (damage to or disease of the kidney)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

n/a

What are the existing conditions these people have? *

Immunodeficiency Disorders: 3 people, 23.08%
Birth Control: 3 people, 23.08%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 23.08%
Premenstrual Syndrome: 2 people, 15.38%
Osteomyelitis Fungal (infection of bone by fungus): 1 person, 7.69%
Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 1 person, 7.69%
Acne (skin problems that cause pimples): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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