Cotrim and Pantosin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cotrim (sulfamethoxazole; trimethoprim) and Pantosin (pantethine). Common drug interactions include cytomegalovirus infection among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Cotrim and Pantosin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Pantosin?

Pantosin has active ingredients of pantethine. eHealthMe is studying from 1,165 Pantosin users. Check the latest studies of Pantosin.



On Jul, 14, 2026

11 people who take Cotrim and Pantosin together, and have interactions are studied.

Cotrim and Pantosin drug interactions.

What are the common drug interactions of Cotrim and Pantosin, by gender? *:

female:

  1. Cytomegalovirus infection
  2. Interstitial lung disease
  3. Oedema peripheral (superficial swelling)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Anaemia (lack of blood)
  6. Aspartate aminotransferase increased
  7. Blood lactate dehydrogenase increased
  8. Bone pain
  9. C-reactive protein increased
  10. Cardiomegaly (increased size of heart than normal)

male:

  1. Platelet count decreased
  2. Lymphocyte count decreased
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Medulloblastoma recurrent (reoccurrence of a fast-growing, high-grade tumour that always begins in the cerebellum)
  5. Meningitis staphylococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
  6. Neoplasm malignant (cancer tumour)
  7. Neoplasm progression (growth of tumour)
  8. Pyrexia (fever)
  9. Retinal vein occlusion (a blockage of the small veins that carry blood away from the retina)
  10. Systemic candida (whole body fungal infection)

What are the common drug interactions of Cotrim and Pantosin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anaemia (lack of blood)
  2. Lymphocyte count decreased
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Medulloblastoma recurrent (reoccurrence of a fast-growing, high-grade tumour that always begins in the cerebellum)
  5. Meningitis staphylococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. Platelet count decreased
  8. Systemic candida (whole body fungal infection)
  9. White blood cell count decreased

10-19:

n/a

20-29:

n/a

30-39:

  1. Upper airway obstruction

40-49:

n/a

50-59:

n/a

60+:

  1. Platelet count decreased
  2. Herpes zoster
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Anaemia (lack of blood)
  5. Aspartate aminotransferase increased
  6. Blood lactate dehydrogenase increased
  7. Bone pain
  8. C-reactive protein increased
  9. Cardiomegaly (increased size of heart than normal)
  10. Constipation

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 8 people, 72.73%
  2. High Blood Pressure: 3 people, 27.27%
  3. Constipation: 3 people, 27.27%
  4. Neuropathy Peripheral (surface nerve damage): 2 people, 18.18%
  5. Insomnia (sleeplessness): 2 people, 18.18%
  6. Herpes Zoster: 2 people, 18.18%
  7. Gastric Ulcer (stomach ulcer): 2 people, 18.18%
  8. Depression: 2 people, 18.18%
  9. Compression Fracture (fracture due to pressure caused by injury): 2 people, 18.18%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and Pantosin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cotrim and Pantosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pantosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cotrim and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pantosin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and pantethine (the active ingredients of Cotrim and Pantosin, respectively), and Cotrim and Pantosin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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