Sumatriptan succinate and Cotrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan succinate (sumatriptan succinate) and Cotrim (sulfamethoxazole; trimethoprim). Common drug interactions include dyspnoea among females and aspartate aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan succinate and Cotrim. It is created by eHealthMe based on reports of 8 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan succinate?

Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

On Jan, 15, 2026

8 people who take Sumatriptan succinate and Cotrim together, and have interactions are studied.

Sumatriptan succinate and Cotrim drug interactions.

What are the common drug interactions of Sumatriptan Succinate and Cotrim, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Aphonia (inability to produce voice)
Cough
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Dizziness
Drug eruption (adverse drug reaction of the skin)
Dysphonia (speech disorder attributable to a disorder of phonation)
Erythema multiforme (a type of hypersensitivity reaction)

male:

Aspartate aminotransferase increased
Blood lactic acid increased
Blood triglycerides increased
Chest pain
Vomiting

What are the common drug interactions of Sumatriptan Succinate and Cotrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Cough
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Drug eruption (adverse drug reaction of the skin)
Erythema multiforme (a type of hypersensitivity reaction)
Malaise (a feeling of general discomfort or uneasiness)
Oedema (fluid collection in tissue)
Pruritus (severe itching of the skin)

40-49:

n/a

50-59:

Aspartate aminotransferase increased
Blood lactic acid increased
Blood triglycerides increased
Chest pain
Vomiting

60+:

Drug level increased
Haemodynamic instability (disturbances in the blood movement in our body)
Oropharyngeal pain
Tinnitus (a ringing in the ears)
Wheezing (a high-pitched whistling sound made while you breath)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Aphonia (inability to produce voice)
Dizziness

* Approximation only. Some reports may have incomplete information.

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