Coumadin and Dexedrine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coumadin (warfarin sodium) and Dexedrine (dextroamphetamine sulfate). Common drug interactions include fatigue among females and collapse among males.

The phase IV clinical study analyzes what interactions people have when they take Coumadin and Dexedrine. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Dexedrine?

Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.



On Jul, 09, 2026

22 people who take Coumadin and Dexedrine together, and have interactions are studied.

Coumadin and Dexedrine drug interactions.

What are the common drug interactions of Coumadin and Dexedrine, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Myalgia (muscle pain)
  4. Oropharyngeal pain
  5. Pain in extremity
  6. Skin ulcer
  7. Abdominal pain lower
  8. Abdominal pain upper
  9. Alopecia (absence of hair from areas of the body)
  10. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)

male:

  1. Collapse (sudden functional breakdown)
  2. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  3. Bacterial infection
  4. Blood creatinine increased
  5. Blood immunoglobulin g increased
  6. Cardiomyopathy (weakening of the heart muscle)
  7. Cellulitis (infection under the skin)
  8. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  9. Dental caries
  10. Dental fistula

What are the common drug interactions of Coumadin and Dexedrine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)
  2. Renal cyst (kidney cyst)
  3. Renal failure chronic (long lasting kidney dysfunction)
  4. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Sinusitis (inflammation of sinus)
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Streptococcal bacteraemia (a bacterial infection of blood)
  9. Tenderness (pain or discomfort when an affected area is touched)
  10. Tooth fracture

60+:

  1. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  2. Collapse (sudden functional breakdown)
  3. Drug hypersensitivity
  4. Myalgia (muscle pain)
  5. Skin ulcer
  6. Blood pressure decreased
  7. Blood pressure increased
  8. Chest discomfort
  9. Chronic kidney disease
  10. Coma (state of unconsciousness lasting more than six hours)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 36.36%
  2. Depression: 5 people, 22.73%
  3. Sleep Disorder: 4 people, 18.18%
  4. Neuropathy Peripheral (surface nerve damage): 4 people, 18.18%
  5. Muscle Aches (muscle pain): 3 people, 13.64%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 13.64%
  7. Libido Decreased (loss of interest in sex): 3 people, 13.64%
  8. High Blood Pressure: 3 people, 13.64%
  9. Bone Disorder: 3 people, 13.64%
  10. Anaemia (lack of blood): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and Dexedrine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coumadin and Dexedrine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dexedrine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coumadin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexedrine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium and dextroamphetamine sulfate (the active ingredients of Coumadin and Dexedrine, respectively), and Coumadin and Dexedrine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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