Coumadin and Lac-hydrin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coumadin (warfarin sodium) and Lac-hydrin (ammonium lactate). Common drug interactions include cardioactive drug level increased among females and embolism venous among males.
The phase IV clinical study analyzes what interactions people have when they take Coumadin and Lac-hydrin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Coumadin?
Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.
What is Lac-hydrin?
Lac-hydrin has active ingredients of ammonium lactate. eHealthMe is studying from 534 Lac-hydrin users. Check the latest studies of Lac-hydrin.
25 people who take Coumadin and Lac-hydrin together, and have interactions are studied.

What are the common drug interactions of Coumadin and Lac-Hydrin, by gender? *:
female:
- Cardioactive drug level increased
- Cardiomegaly (increased size of heart than normal)
- Cataract (clouding of the lens inside the eye)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Drug ineffective
- Dry mouth
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Endometrial neoplasm (tumour of uterus wall)
- Anxiety
- Depression
male:
- Embolism venous (embolus may pass into the arterial system)
- Haematuria (presence of blood in urine)
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Staphylococcal bacteraemia (a bacterial infection of blood)
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Vomiting
- Pulmonary embolism (blockage of the main artery of the lung)
- Rectal haemorrhage (bleeding from anus)
What are the common drug interactions of Coumadin and Lac-Hydrin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Restlessness (not able to rest)
- Sensation of pressure
- Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
- Ventricular failure (heart failure)
- Chest discomfort
- Cough
- Dyspepsia (indigestion)
- Heart rate irregular
- Nasopharyngitis (inflammation of the nasopharynx)
- Oedema (fluid collection in tissue)
50-59:
- Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
- Pulmonary embolism (blockage of the main artery of the lung)
- Dehydration (dryness resulting from the removal of water)
- Headache (pain in head)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Depression
- Gallbladder disorder
- Neuropathic arthropathy (a progressive destruction of bone and joints)
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Abscess (pus)
60+:
- Abdominal discomfort
- Dehydration (dryness resulting from the removal of water)
- Drug ineffective
- Dry mouth
- Duodenal ulcer
- Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haematemesis (vomiting of blood)
- Haemoglobin decreased
What are the existing conditions these people have? *
- Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 12.00%
- Pain: 3 people, 12.00%
- Nausea (feeling of having an urge to vomit): 3 people, 12.00%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 12.00%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 8.00%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 8.00%
- Constipation: 2 people, 8.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Coumadin and Lac-hydrin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Coumadin (133,228 reports)
- Lac-hydrin (534 reports)
Browse all drug interactions of Coumadin and Lac-hydrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coumadin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lac-hydrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coumadin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lac-hydrin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on warfarin sodium and ammonium lactate (the active ingredients of Coumadin and Lac-hydrin, respectively), and Coumadin and Lac-hydrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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