Coumadin and Robinul drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coumadin (warfarin sodium) and Robinul (glycopyrrolate). Common drug interactions include renal injury among females and red blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Coumadin and Robinul. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

36 people who take Coumadin and Robinul together, and have interactions are studied.

Coumadin and Robinul drug interactions.

What are the common drug interactions of Coumadin and Robinul, by gender? *:

female:

  1. Renal injury (kidney injury)
  2. Abdominal pain upper
  3. Dyspnoea (difficult or laboured respiration)
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Laryngitis (inflammation of the larynx)
  6. Ligament sprain (ligament stretched)
  7. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Nausea (feeling of having an urge to vomit)
  9. Osteonecrosis (death of bone)
  10. Speech disorder

male:

  1. Red blood cell count decreased
  2. Pain
  3. Dysstasia (difficulty in standing)
  4. Fatigue (feeling of tiredness)
  5. Fluid retention (an abnormal accumulation of fluid in the blood)
  6. Hemiplegia (paralysis of one side of the body)
  7. Ill-defined disorder
  8. Immobile (not moving)
  9. Incontinence (lack of moderation or self-control)
  10. Nocturia (the need to get up in the night to urinate)

What are the common drug interactions of Coumadin and Robinul, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chest pain
  2. Dyspnoea exertional (breathlessness or shortness of breath)
  3. Fatigue (feeling of tiredness)

50-59:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Peripheral coldness

60+:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anaemia (lack of blood)
  4. Arthralgia (joint pain)
  5. Balance disorder
  6. Bone disorder
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Disability
  9. Ear infection
  10. Excoriation (to tear or wear off the skin of)

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 16.67%
  2. Diabetes: 3 people, 8.33%
  3. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 8.33%
  4. Rashes (redness): 2 people, 5.56%
  5. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and Robinul?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coumadin and Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coumadin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robinul and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium and glycopyrrolate (the active ingredients of Coumadin and Robinul, respectively), and Coumadin and Robinul (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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