Coumadin and Tobi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coumadin (warfarin sodium) and Tobi (tobramycin). Common drug interactions include decreased interest among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Coumadin and Tobi. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Tobi?

Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.

On Jul, 10, 2026

13 people who take Coumadin and Tobi together, and have interactions are studied.

What are the common drug interactions of Coumadin and Tobi, by gender? *:

female:

Decreased interest
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dehydration (dryness resulting from the removal of water)
Dental caries
Depression
Dermal cyst
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Device failure
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

male:

Dyspnoea (difficult or laboured respiration)
Pneumonia
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Haematocrit decreased
Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Lymphocyte count decreased
Malaise (a feeling of general discomfort or uneasiness)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

What are the common drug interactions of Coumadin and Tobi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Anaemia (lack of blood)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Asthenia (weakness)
Blood lactate dehydrogenase decreased
Disease progression
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Haemoglobinuria (the presence of free haemoglobin in the urine)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Insomnia (sleeplessness)
Tremor (trembling or shaking movements in one or more parts of your body)
Urine output increased
Ear disorder
Feeling jittery
Headache (pain in head)

60+:

Dyspnoea (difficult or laboured respiration)
Pneumonia
Blood glucose increased
Blood urea increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dysphagia (a condition in which swallowing is difficult or painful)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Haematocrit decreased
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 4 people, 30.77%
Cystic Fibrosis (disease of the secretary glands): 3 people, 23.08%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 7.69%
Prostatic Specific Antigen Increased: 1 person, 7.69%
Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 1 person, 7.69%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 7.69%
Dyspnea (difficult or laboured breathing): 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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