Cozaar and Duopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Duopa (carbidopa; levodopa). Common drug interactions include death among females and device expulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Duopa. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Duopa?

Duopa has active ingredients of carbidopa; levodopa. eHealthMe is studying from 8,208 Duopa users. Check the latest studies of Duopa.



On Jul, 19, 2026

16 people who take Cozaar and Duopa together, and have interactions are studied.

Cozaar and Duopa drug interactions.

What are the common drug interactions of Cozaar and Duopa, by gender? *:

female:

  1. Death
  2. Infection
  3. Urinary tract infection
  4. Adverse event
  5. Confusional state
  6. Fall
  7. Fractured coccyx (fracture tail bone)

male:

  1. Device expulsion
  2. Mobility decreased (ability to move is reduced)
  3. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  4. Fungal skin infection
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  7. Pain in extremity
  8. Anxiety
  9. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  10. Cardiac failure chronic

What are the common drug interactions of Cozaar and Duopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  2. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  3. Cough
  4. Dyspnoea (difficult or laboured respiration)
  5. Heart injury
  6. Hypotension (abnormally low blood pressure)
  7. Inflammation
  8. Influenza
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

  1. Pneumonia
  2. Device expulsion
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Infection
  5. Influenza
  6. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  7. Pain in extremity
  8. Urinary tract infection
  9. Adverse event
  10. Cardiac failure chronic

What are the existing conditions these people have? *

  1. Parkinson's Disease: 12 people, 75.00%
  2. Sleep Disorder: 2 people, 12.50%
  3. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
  4. Stress And Anxiety: 1 person, 6.25%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.25%
  6. Hypersensitivity: 1 person, 6.25%
  7. Dry Skin: 1 person, 6.25%
  8. Depression: 1 person, 6.25%
  9. Constipation: 1 person, 6.25%
  10. Cardiac Disorder: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and Duopa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cozaar and Duopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and carbidopa; levodopa (the active ingredients of Cozaar and Duopa, respectively), and Cozaar and Duopa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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