Cozaar and Minitran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Minitran (nitroglycerin). Common drug interactions include joint swelling among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Minitran. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Minitran?

Minitran has active ingredients of nitroglycerin. eHealthMe is studying from 950 Minitran users. Check the latest studies of Minitran.



On Jul, 16, 2026

14 people who take Cozaar and Minitran together, and have interactions are studied.

Cozaar and Minitran drug interactions.

What are the common drug interactions of Cozaar and Minitran, by gender? *:

female:

  1. Joint swelling
  2. Nausea (feeling of having an urge to vomit)
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  4. Back pain
  5. Blood sodium decreased
  6. Chronic kidney disease
  7. Confusional state
  8. Constipation
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Cough
  3. Blood lactate dehydrogenase increased
  4. Blood myoglobin increased
  5. Bradycardia (abnormally slow heart action)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Chest pain
  8. Diabetes mellitus inadequate control
  9. Dry skin
  10. Dysphonia (speech disorder attributable to a disorder of phonation)

What are the common drug interactions of Cozaar and Minitran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Abdominal pain upper
  3. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  4. Anxiety
  5. Aortic atherosclerosis (degenerative process of aortic arteries)
  6. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  7. Blood cholesterol increased
  8. Bradycardia (abnormally slow heart action)
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Chest pain

60+:

  1. Joint swelling
  2. Nausea (feeling of having an urge to vomit)
  3. Constipation
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Cough
  6. Dehydration (dryness resulting from the removal of water)
  7. Dizziness
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Fall

What are the existing conditions these people have? *

  1. Diabetes: 2 people, 14.29%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.14%
  3. Thyroid Diseases: 1 person, 7.14%
  4. Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
  5. Lung Infection: 1 person, 7.14%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
  7. Dizziness: 1 person, 7.14%
  8. Depression: 1 person, 7.14%
  9. Conjunctivitis Infective (infection of the conjunctiva): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and Minitran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cozaar and Minitran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Minitran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Minitran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and nitroglycerin (the active ingredients of Cozaar and Minitran, respectively), and Cozaar and Minitran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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