Cozaar and Narcan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Narcan (naloxone hydrochloride). Common drug interactions include constipation among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Narcan. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

On Aug, 03, 2026

58 people who take Cozaar and Narcan together, and have interactions are studied.

What are the common drug interactions of Cozaar and Narcan, by gender? *:

female:

Constipation
Cough
Decreased activity
Depression
Dizziness (excl vertigo)
Emotional distress
Excessive bronchial secretion
Feeling drunk
Female genital tract fistula (passage in genital tract of female)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Death
Anxiety
Fatigue (feeling of tiredness)
Hangover
Hunger
Hyperhidrosis (abnormally increased sweating)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Insomnia (sleeplessness)
Loss of consciousness
Renal injury (kidney injury)

What are the common drug interactions of Cozaar and Narcan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Immunodeficiency
Nausea (feeling of having an urge to vomit)
Pancreatic atrophy
Pyrexia (fever)
Staphylococcus test positive
Urinary tract infection

10-19:

n/a

20-29:

Chest pain
Atrial thrombosis (blood clot that develops in an artery)

30-39:

Abdominal hernia
Small intestinal obstruction (blockage in small intestine)
Back pain
Muscle spasms (muscle contraction)

40-49:

Pain
Acute respiratory failure
Asthenia (weakness)
Death
Diastolic dysfunction
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Generalised oedema (swelling all over the body)
Hepatic lesion

50-59:

Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Cardiac arrest
Confusional state
Fall
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pain in extremity
Pericardial effusion (fluid around the heart)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)

60+:

Death
Renal failure (kidney dysfunction)
Cough
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Renal injury (kidney injury)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal abscess (collection of pus in abdomen)
Abnormal behaviour
Anxiety

What are the existing conditions these people have? *

Pain: 13 people, 22.41%
Nausea (feeling of having an urge to vomit): 8 people, 13.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 13.79%
Dyspnea (difficult or laboured breathing): 7 people, 12.07%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 10.34%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 8.62%
Overdose: 5 people, 8.62%
High Blood Cholesterol: 5 people, 8.62%
Neck Pain: 4 people, 6.90%
Constipation: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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