Cozaar and Remodulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Remodulin (treprostinil sodium). Common drug interactions include cardiac failure acute among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Remodulin. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Remodulin?

Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,843 Remodulin users. Check the latest studies of Remodulin.

On Aug, 09, 2026

48 people who take Cozaar and Remodulin together, and have interactions are studied.

What are the common drug interactions of Cozaar and Remodulin, by gender? *:

female:

Cardiac failure acute
Catheter site erythema (redness of skin at catheter site)
Catheter site pain
Dysphagia (a condition in which swallowing is difficult or painful)
Epistaxis (bleed from the nose)
Flushing (the warm, red condition of human skin)
Heart rate increased
Hypoacusis (loss of hearing)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

male:

Fatigue (feeling of tiredness)
Headache (pain in head)
Infusion site pain
Pleural effusion (water on the lungs)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dizziness

What are the common drug interactions of Cozaar and Remodulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Dyspnoea (difficult or laboured respiration)
Dizziness
Oedema peripheral (superficial swelling)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Grunting (abnormal, short, deep, hoarse sounds in exhalation that often accompany severe chest pain)

40-49:

Headache (pain in head)
Infusion site pain
Limb discomfort (discomfort in leg)
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Pneumonia
Pruritus (severe itching of the skin)
Rash
Skin discolouration (change of skin colour)
Sluggishness (lacking alertness)

50-59:

Bradycardia (abnormally slow heart action)
Dizziness postural
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Infusion site pain
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Influenza
Anaemia (lack of blood)
Catheter site erythema (redness of skin at catheter site)
Death
Vomiting
Dizziness
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 10 people, 20.83%
High Blood Cholesterol: 4 people, 8.33%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 3 people, 6.25%
Nausea (feeling of having an urge to vomit): 3 people, 6.25%
Diarrhea: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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