Crixivan and Odefsey drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crixivan (indinavir sulfate) and Odefsey (emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate). Common drug interactions include anhedonia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Crixivan and Odefsey. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

What is Odefsey?

Odefsey has active ingredients of emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 4,605 Odefsey users. Check the latest studies of Odefsey.

On Jul, 02, 2026

27 people who take Crixivan and Odefsey together, and have interactions are studied.

What are the common drug interactions of Crixivan and Odefsey, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Blood creatinine increased
Bone density decreased
Depression
Vitamin d deficiency

male:

Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)
Upper limb fracture
Ankle fracture
Arthralgia (joint pain)
Blood creatinine increased
Mobility decreased (ability to move is reduced)
Dysstasia (difficulty in standing)

What are the common drug interactions of Crixivan and Odefsey, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Ankle fracture
Arthralgia (joint pain)
Depression
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Upper limb fracture
Bone density decreased
Depression
Exercise tolerance decreased
Multiple fractures
Multiple injuries
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Renal impairment (severely reduced kidney function)

* Approximation only. Some reports may have incomplete information.

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