Cryselle and Fluoxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cryselle (ethinyl estradiol; norgestrel) and Fluoxetine (fluoxetine hydrochloride). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Cryselle and Fluoxetine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Cryselle?

Cryselle has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 673 Cryselle users. Check the latest studies of Cryselle.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,824 Fluoxetine users. Check the latest studies of Fluoxetine.

On Aug, 09, 2026

16 people who take Cryselle and Fluoxetine together, and have interactions are studied.

Cryselle and Fluoxetine drug interactions.

What are the common drug interactions of Cryselle and Fluoxetine, by gender? *:

female:

Migraine (headache)
Cough
Paranasal sinus discomfort
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Productive cough
Pruritus (severe itching of the skin)
Rhinorrhoea (watery mucus discharge from the nose)
Sinusitis (inflammation of sinus)
Skin infection
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

male:

n/a

What are the common drug interactions of Cryselle and Fluoxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)

30-39:

Oral herpes (viral infection of mouth)
Paranasal sinus discomfort
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Productive cough
Pruritus (severe itching of the skin)
Rhinorrhoea (watery mucus discharge from the nose)
Sinusitis (inflammation of sinus)
Skin infection
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Uterine infection

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Lipidosis (disorder of lipid metabolism involving abnormal accumulation of lipids in the reticuloendothelial cells): 6 people, 37.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 25.00%
Immunodeficiency Common Variable: 4 people, 25.00%
Immunodeficiency: 4 people, 25.00%
Thyroid Diseases: 2 people, 12.50%
Multiple Allergies (allergy to multiple agents): 2 people, 12.50%
Headache (pain in head): 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
Stress And Anxiety: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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