Cryselle and Yaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cryselle (ethinyl estradiol; norgestrel) and Yaz (drospirenone; ethinyl estradiol). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Cryselle and Yaz. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cryselle?

Cryselle has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 673 Cryselle users. Check the latest studies of Cryselle.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

On Jul, 14, 2026

13 people who take Cryselle and Yaz together, and have interactions are studied.

What are the common drug interactions of Cryselle and Yaz, by gender? *:

female:

Pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal pain upper
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Abdominal pain
Abscess intestinal (collections of pus-intestinal)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

n/a

What are the common drug interactions of Cryselle and Yaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pain
Cholecystitis (infection of gallbladder)
Gallbladder disorder
Injury
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gallbladder injury

30-39:

Pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Abdominal pain
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis (infection of gallbladder)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Gastrointestinal injury (injury to gastrointestinal tract)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Inflammatory bowel disease
Intestinal obstruction
Irritable bowel syndrome
Polyp
Psoriasis (immune-mediated disease that affects the skin)
Injury

60+:

n/a

What are the existing conditions these people have? *

Pain: 3 people, 23.08%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 15.38%
Menstruation Irregular: 2 people, 15.38%
High Blood Cholesterol: 2 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 15.38%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 7.69%
Nausea And Vomiting: 1 person, 7.69%
Joint Pain: 1 person, 7.69%
Irritable Bowel Syndrome: 1 person, 7.69%
Gastrointestinal Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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