Cubicin and Opdivo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cubicin (daptomycin) and Opdivo (nivolumab). Common drug interactions include encephalitis among females.

The phase IV clinical study analyzes what interactions people have when they take Cubicin and Opdivo. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cubicin?

Cubicin has active ingredients of daptomycin. It is often used in infection. eHealthMe is studying from 7,991 Cubicin users. Check the latest studies of Cubicin.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

On Aug, 06, 2026

13 people who take Cubicin and Opdivo together, and have interactions are studied.

What are the common drug interactions of Cubicin and Opdivo, by gender? *:

female:

Encephalitis (inflammation of the brain)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Rash
Secondary adrenocortical insufficiency (inadequate secretion of acth by the pituitary gland)
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults)
Malignant neoplasm progression (cancer tumour came back)
Pemphigoid (tense blisters on the skin)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Heparin-induced thrombocytopenia

male:

n/a

What are the common drug interactions of Cubicin and Opdivo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults)
Malignant neoplasm progression (cancer tumour came back)
Pemphigoid (tense blisters on the skin)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

Encephalitis (inflammation of the brain)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Rash
Secondary adrenocortical insufficiency (inadequate secretion of acth by the pituitary gland)
Heparin-induced thrombocytopenia
Skin disorder (skin disease)
Type 1 diabetes mellitus
Nephritis (inflammation of the nephrons in the kidneys)
Pancreatitis (inflammation of pancreas)
Staphylococcal infection (an infection with staphylococcus bacteria)

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 6 people, 46.15%
Gastric Cancer (stomach cancer): 6 people, 46.15%
Thyrotoxic Crisis (a life threatening condition due to excess secretion of thyroid hormone): 4 people, 30.77%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 30.77%
Metastases To Lung (cancer spreads to lung): 4 people, 30.77%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 30.77%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 15.38%
Pleural Effusion (water on the lungs): 2 people, 15.38%
Pemphigoid (tense blisters on the skin): 2 people, 15.38%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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