Curcumin and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Curcumin (turmeric) and Advil (ibuprofen). Common drug interactions include fatigue among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Curcumin and Advil. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Curcumin?

Curcumin has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 3,677 Curcumin users. Check the latest studies of Curcumin.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

62 people who take Curcumin and Advil together, and have interactions are studied.

What are the common drug interactions of Curcumin and Advil, by gender? *:

female:

Fatigue (feeling of tiredness)
Rash
Dizziness
Hypoaesthesia (reduced sense of touch or sensation)
Arthralgia (joint pain)
Constipation
Back pain
Neuropathy peripheral (surface nerve damage)
Pain in extremity
Abdominal pain upper

male:

Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Oropharyngeal discomfort (pain or irritation of oropharynx)
Pulse absent
Rash
Red blood cell sedimentation rate increased
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Stomatitis (inflammation of mucous membrane of mouth)
Tremor (trembling or shaking movements in one or more parts of your body)
C-reactive protein increased

What are the common drug interactions of Curcumin and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Blood pressure diastolic increased
Blood pressure increased
Cellulitis (infection under the skin)
Constipation
Dizziness
Drug ineffective
Ear infection
Ear pain
Fatigue (feeling of tiredness)

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Arthralgia (joint pain)
Back pain
Exostosis (formation of new bone on the surface of a bone)
Intervertebral disc degeneration (spinal disc degeneration)
Joint stiffness
Mumps (a virus that can lead to swelling and pain in the salivary glands, along with fever, loss of appetite, and fatigue)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Neuralgia (pain in one or more nerves)

50-59:

Muscle fatigue (a condition in which muscles cannot exert their normal force)
Muscle spasms (muscle contraction)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Pneumonia
Post-traumatic neck syndrome
Pyrexia (fever)

60+:

Cough
Fatigue (feeling of tiredness)
Abdominal discomfort
Abdominal distension
Abdominal pain upper
Abnormal behaviour
Adverse drug reaction
Agitation (state of anxiety or nervous excitement)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 16 people, 25.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.06%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 8.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 8.06%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 5 people, 8.06%

* Approximation only. Some reports may have incomplete information.

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