Curcumin and Augmentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Curcumin (turmeric) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include epistaxis among females and infusion site infection among males.

The phase IV clinical study analyzes what interactions people have when they take Curcumin and Augmentin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Curcumin?

Curcumin has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 3,676 Curcumin users. Check the latest studies of Curcumin.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.



On Jul, 31, 2026

25 people who take Curcumin and Augmentin together, and have interactions are studied.

Curcumin and Augmentin drug interactions.

What are the common drug interactions of Curcumin and Augmentin, by gender? *:

female:

  1. Epistaxis (bleed from the nose)
  2. Dyspnoea (difficult or laboured respiration)
  3. Ear infection
  4. Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances))
  5. Aural polyp (growth in the outside (external) ear canal)
  6. Bronchial obstruction (blockage of the breathing passages to the lungs)
  7. Chest pain
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Dizziness
  10. Dry mouth

male:

  1. Infusion site infection
  2. Bladder cancer
  3. Urinary sediment present
  4. Asthenia (weakness)
  5. Death
  6. Diarrhoea
  7. Retching (strong involuntary effort to vomit)
  8. Vomiting
  9. Head discomfort
  10. Parosmia (distortion of the sense of smell, as in smelling odours that are not present)

What are the common drug interactions of Curcumin and Augmentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Electrocardiogram t wave inversion
  2. Bronchial obstruction (blockage of the breathing passages to the lungs)
  3. Chest pain
  4. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  5. Granuloma (a small area of inflammation due to tissue injury)
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Headache (pain in head)
  8. Hilar lymphadenopathy (disease of the lymph nodes due to infection)
  9. Hypermetabolism (abnormal increase in the body's basal metabolic rate)
  10. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)

40-49:

n/a

50-59:

n/a

60+:

  1. Bladder cancer
  2. Epistaxis (bleed from the nose)
  3. Dizziness
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Retching (strong involuntary effort to vomit)
  8. Vomiting
  9. Thrombosis (formation of a blood clot inside a blood vessel)
  10. Weight decreased

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 7 people, 28.00%
  2. Immunodeficiency Common Variable: 6 people, 24.00%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.00%
  4. Constipation: 3 people, 12.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
  6. Haemorrhage (bleeding): 3 people, 12.00%
  7. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 12.00%
  8. Headache (pain in head): 3 people, 12.00%
  9. High Blood Pressure: 3 people, 12.00%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Curcumin and Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Curcumin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Curcumin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on turmeric and amoxicillin; clavulanate potassium (the active ingredients of Curcumin and Augmentin, respectively), and Curcumin and Augmentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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