Curcumin and Methylfolate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Curcumin (turmeric) and Methylfolate (folic acid). Common drug interactions include sinusitis among females.
The phase IV clinical study analyzes what interactions people have when they take Curcumin and Methylfolate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Curcumin?
Curcumin has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 3,676 Curcumin users. Check the latest studies of Curcumin.
What is Methylfolate?
Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.
11 people who take Curcumin and Methylfolate together, and have interactions are studied.

What are the common drug interactions of Curcumin and Methylfolate, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Agitation (state of anxiety or nervous excitement)
- Limb injury
- Mania (a state of abnormally elevated or irritable mood)
- Memory impairment
- Neurotransmitter level altered
- Oedema (fluid collection in tissue)
- Rash pruritic (redness with itching)
- Sedation
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
male:
n/a
What are the common drug interactions of Curcumin and Methylfolate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Agitation (state of anxiety or nervous excitement)
- Apnoea (suspension of external breathing)
- Cerebral disorder (brain disease)
- Daydreaming
- Drug dependence
- Eyelid ptosis (falling of the upper or lower eyelid)
- Feeling hot
- General physical health deterioration (weak health status)
- Headache (pain in head)
- Insomnia (sleeplessness)
40-49:
- Drug dependence
- Drug ineffective
- Feeling hot
- General physical health deterioration (weak health status)
- Headache (pain in head)
- Insomnia (sleeplessness)
- Mania (a state of abnormally elevated or irritable mood)
- Memory impairment
- Neurotransmitter level altered
- Sedation
50-59:
n/a
60+:
- Fall
- Limb injury
- Nephrolithiasis (calculi in the kidneys)
- Oedema (fluid collection in tissue)
- Rash pruritic (redness with itching)
- Sinusitis (inflammation of sinus)
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
What are the existing conditions these people have? *
- Sleep Disorder: 3 people, 27.27%
- Injury: 3 people, 27.27%
- Agitation (state of anxiety or nervous excitement): 3 people, 27.27%
- Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 27.27%
- Blood Glucose Abnormal: 3 people, 27.27%
- Depression: 3 people, 27.27%
- Diabetes: 3 people, 27.27%
- Feeling Abnormal: 3 people, 27.27%
- Sedation: 3 people, 27.27%
- High Blood Cholesterol: 3 people, 27.27%
* Approximation only. Some reports may have incomplete information.
Do you take Curcumin and Methylfolate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Curcumin (3,676 reports)
- Methylfolate (1,018 reports)
Browse all drug interactions of Curcumin and Methylfolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Curcumin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methylfolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Curcumin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylfolate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on turmeric and folic acid (the active ingredients of Curcumin and Methylfolate, respectively), and Curcumin and Methylfolate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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