Cyclophosphamide and Aripiprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyclophosphamide (cyclophosphamide) and Aripiprazole (aripiprazole). Common drug interactions include neurotoxicity among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Cyclophosphamide and Aripiprazole. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

On Jul, 14, 2026

86 people who take Cyclophosphamide and Aripiprazole together, and have interactions are studied.

Cyclophosphamide and Aripiprazole drug interactions.

What are the common drug interactions of Cyclophosphamide and Aripiprazole, by gender? *:

female:

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Platelet count decreased
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Psychotic disorder
Pulmonary haemorrhage (acute bleeding from the lung)
Respiratory rate increased (excess breathing rate/min)
Second primary malignancy (after getting cure a cancer, a new cancer development)
Serum ferritin increased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

Drug ineffective
Leukopenia (less number of white blood cells in blood)
Chronic kidney disease
Rebound effect (take-back effect)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Aphasia (damage to the parts of the brain that control language)
Headache (pain in head)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Muscular weakness (muscle weakness)

What are the common drug interactions of Cyclophosphamide and Aripiprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Headache (pain in head)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

10-19:

Drug ineffective
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Hypotension (abnormally low blood pressure)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

20-29:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Unresponsive to stimuli
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Aphasia (damage to the parts of the brain that control language)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood glucose increased
Blood lactate dehydrogenase increased
Blood urea increased
Drug ineffective

30-39:

Febrile neutropenia (fever with reduced white blood cells)
Psychotic disorder
Second primary malignancy (after getting cure a cancer, a new cancer development)

40-49:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Agitation (state of anxiety or nervous excitement)
Arachnoid cyst
Cerebral atrophy (decrement in size of brain)
Depressed mood
Disturbance in attention
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Enterococcal infection
Febrile neutropenia (fever with reduced white blood cells)
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)

50-59:

Back pain
Chills (felling of cold)
Incontinence (lack of moderation or self-control)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pyrexia (fever)
Stress
Agitation (state of anxiety or nervous excitement)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alopecia (absence of hair from areas of the body)
Cardiac disorder

60+:

Pneumonia
Chronic kidney disease
Renal failure (kidney dysfunction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaemia (lack of blood)
Clostridium test positive
Cytomegalovirus colitis (an inflammation of the colon from virus)
Diarrhoea
Herpes zoster
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 21 people, 24.42%
Burkitt Lymphoma (cancer of the lymphatic system): 21 people, 24.42%
Psychotic Disorder: 18 people, 20.93%
Breast Cancer: 18 people, 20.93%
Constipation: 15 people, 17.44%
Breast Cancer Female: 14 people, 16.28%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 11 people, 12.79%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 10 people, 11.63%
Gastric Ulcer (stomach ulcer): 10 people, 11.63%
Affective Disorder (mental disorder): 10 people, 11.63%

* Approximation only. Some reports may have incomplete information.

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