Cyclophosphamide and Flurbiprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyclophosphamide (cyclophosphamide) and Flurbiprofen (flurbiprofen). Common drug interactions include febrile neutropenia among females and hypocalcaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cyclophosphamide and Flurbiprofen. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is often used in rheumatoid arthritis. eHealthMe is studying from 2,677 Flurbiprofen users. Check the latest studies of Flurbiprofen.

On Jul, 09, 2026

37 people who take Cyclophosphamide and Flurbiprofen together, and have interactions are studied.

Cyclophosphamide and Flurbiprofen drug interactions.

What are the common drug interactions of Cyclophosphamide and Flurbiprofen, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Altered state of consciousness (altered state of mind)
Pneumonia
Stomatitis (inflammation of mucous membrane of mouth)
Thrombocytopenia (decrease of platelets in blood)
Neutropenia (an abnormally low number of neutrophils)
Cerebral haemorrhage (bleeding within the brain)
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer)
Drug eruption (adverse drug reaction of the skin)
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)

male:

Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Myelosuppression (a decrease in the production of blood cells)
Nasopharyngitis (inflammation of the nasopharynx)
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oedema peripheral (superficial swelling)
Oral infection
Platelet count decreased

What are the common drug interactions of Cyclophosphamide and Flurbiprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebral haemorrhage (bleeding within the brain)
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Infection
Enterococcal infection
Enterococcal sepsis
Neuroblastoma (a cancer that forms in your nerve tissue)

10-19:

n/a

20-29:

Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Blood glucose increased
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Myelosuppression (a decrease in the production of blood cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

30-39:

Cerebral haemorrhage (bleeding within the brain)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Venoocclusive liver disease (small veins in the liver are obstructed)

40-49:

Pyrexia (fever)
Blood beta-d-glucan increased
Cystitis haemorrhagic (blood in the urine and painful voiding)
Haematuria (presence of blood in urine)
Haemoglobin decreased
Hydronephrosis (water inside the kidney)
Nasopharyngitis (inflammation of the nasopharynx)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Oral infection

50-59:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Altered state of consciousness (altered state of mind)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Symptom masked
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Drug ineffective
Pneumonia
Stomatitis (inflammation of mucous membrane of mouth)
Thrombocytopenia (decrease of platelets in blood)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Fever: 14 people, 37.84%
Hepatic Function Abnormal: 10 people, 27.03%
Hypersensitivity: 8 people, 21.62%
Insomnia (sleeplessness): 8 people, 21.62%
High Blood Pressure: 7 people, 18.92%
Constipation: 7 people, 18.92%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 18.92%
Myelosuppression (a decrease in the production of blood cells): 6 people, 16.22%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 6 people, 16.22%
Allergies: 6 people, 16.22%

* Approximation only. Some reports may have incomplete information.

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