Cyclophosphamide and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyclophosphamide (cyclophosphamide) and Lanoxin (digoxin). Common drug interactions include hepatitis among females and duodenitis among males.

The phase IV clinical study analyzes what interactions people have when they take Cyclophosphamide and Lanoxin. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.



On Aug, 07, 2026

55 people who take Cyclophosphamide and Lanoxin together, and have interactions are studied.

Cyclophosphamide and Lanoxin drug interactions.

What are the common drug interactions of Cyclophosphamide and Lanoxin, by gender? *:

female:

  1. Hepatitis (inflammation of the liver)
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Neoplasm malignant (cancer tumour)
  4. Sick sinus syndrome (a collection of heart rhythm disorders)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Constipation
  7. Diarrhoea
  8. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  9. Intervertebral disc protrusion (spinal disc protrusion)
  10. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

male:

  1. Duodenitis (inflammation of the duodenum)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
  4. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  5. Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  6. Constipation
  7. Cough
  8. Death
  9. Diarrhoea
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Cyclophosphamide and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  2. Death
  3. Diarrhoea
  4. Hypotension (abnormally low blood pressure)
  5. Lung disorder (lung disease)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

10-19:

  1. Encephalopathy (functioning of the brain is affected by some agent or condition)
  2. Hypotension (abnormally low blood pressure)
  3. Pyrexia (fever)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

20-29:

n/a

30-39:

n/a

40-49:

  1. Febrile neutropenia (fever with reduced white blood cells)

50-59:

  1. Cardiac failure congestive
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Weight increased

60+:

  1. Pneumonia
  2. Pleural effusion (water on the lungs)
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Arthropathy
  5. Asthenia (weakness)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Bacterial test positive
  8. Bone density decreased
  9. Bone disorder
  10. Cardiac arrest

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 30 people, 54.55%
  2. Depression: 24 people, 43.64%
  3. High Blood Pressure: 20 people, 36.36%
  4. Constipation: 16 people, 29.09%
  5. Oral Candidiasis (fungal infection of mouth): 16 people, 29.09%
  6. Nausea (feeling of having an urge to vomit): 16 people, 29.09%
  7. Joint Pain: 15 people, 27.27%
  8. Indigestion: 15 people, 27.27%
  9. Oesophageal Spasm (contraction of oesophagus): 15 people, 27.27%
  10. Mucosal Inflammation (infection of mucous membrane): 15 people, 27.27%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cyclophosphamide and Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide and digoxin (the active ingredients of Cyclophosphamide and Lanoxin, respectively), and Cyclophosphamide and Lanoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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