Cyclophosphamide and Mirapex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyclophosphamide (cyclophosphamide) and Mirapex (pramipexole dihydrochloride). Common drug interactions include dystonia among females and light chain analysis increased among males.

The phase IV clinical study analyzes what interactions people have when they take Cyclophosphamide and Mirapex. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.



On Jul, 19, 2026

18 people who take Cyclophosphamide and Mirapex together, and have interactions are studied.

Cyclophosphamide and Mirapex drug interactions.

What are the common drug interactions of Cyclophosphamide and Mirapex, by gender? *:

female:

  1. Dystonia (abnormal muscle tone)
  2. Dysuria (painful or difficult urination)
  3. Emotional distress
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  5. Epicondylitis (tennis elbow)
  6. Exostosis (formation of new bone on the surface of a bone)
  7. Facet joint syndrome (problem with movement of the facet joints of the spine)
  8. Fracture nonunion (permanent failure of healing following a broken bone)
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Light chain analysis increased
  2. Paraproteinaemia (normal or abnormal plasma protein appearing in large quantities)
  3. Cholecystitis (infection of gallbladder)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Diarrhoea
  6. Febrile neutropenia (fever with reduced white blood cells)
  7. Haematocrit decreased
  8. Haemoglobin decreased
  9. Hepatic failure (liver failure)
  10. Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the common drug interactions of Cyclophosphamide and Mirapex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hypokalaemia (low potassium)
  2. Hypophagia (reduced food intake)
  3. Insomnia (sleeplessness)
  4. Lacrimation increased
  5. Limb injury
  6. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  7. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  8. Lymphadenopathy (disease or enlargement of lymph nodes)
  9. Malignant neoplasm progression (cancer tumour came back)
  10. Mass

60+:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Fatigue (feeling of tiredness)
  3. Haemoglobin decreased
  4. Infection
  5. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Nocturia (the need to get up in the night to urinate)
  8. Oropharyngeal pain
  9. Pelvic fracture
  10. Pneumonia

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 22.22%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 16.67%
  3. Breast Cancer Female: 3 people, 16.67%
  4. Depression: 3 people, 16.67%
  5. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 3 people, 16.67%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
  7. Pain: 2 people, 11.11%
  8. Stress And Anxiety: 2 people, 11.11%
  9. Headache (pain in head): 1 person, 5.56%
  10. Asthma: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cyclophosphamide and Mirapex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mirapex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirapex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide and pramipexole dihydrochloride (the active ingredients of Cyclophosphamide and Mirapex, respectively), and Cyclophosphamide and Mirapex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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