Cymbalta and Coca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cymbalta (duloxetine hydrochloride) and Coca (coca). Common drug interactions include dysphoria among females and substance abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Cymbalta and Coca. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,976 Cymbalta users. Check the latest studies of Cymbalta.

What is Coca?

Coca has active ingredients of coca. eHealthMe is studying from 6,072 Coca users. Check the latest studies of Coca.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

25 people who take Cymbalta and Coca together, and have interactions are studied.

What are the common drug interactions of Cymbalta and Coca, by gender? *:

female:

Dysphoria (generalized dissatisfaction with life)
Dysstasia (difficulty in standing)
Fall
Fatigue (feeling of tiredness)
Haematoma (collection of blood outside the blood vessels)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Irritability
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)

male:

Substance abuse
Overdose
Euphoric mood (excessively happy but may become angry or irritable)
General physical health deterioration (weak health status)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Overweight
Pallor

What are the common drug interactions of Cymbalta and Coca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug abuse
Drug abuser
Drug dependence
Insomnia (sleeplessness)
Respiratory failure (inadequate gas exchange by the respiratory system)
Tourette's disorder (a neurological disorder characterized by repetitive, stereotyped, involuntary movements and vocalizations called tics)
Mania (a state of abnormally elevated or irritable mood)
Overdose
Anxiety disorder

30-39:

Loss of consciousness
Suicide attempt
Agitation (state of anxiety or nervous excitement)
Csf white blood cell count increased
Delirium (wild excitement)
Hallucination (an experience involving the perception of something not present)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

40-49:

Suicidal ideation
Overdose
Drug dependence
Substance abuse
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Asthenia (weakness)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug abuse
Emotional distress
Euphoric mood (excessively happy but may become angry or irritable)

50-59:

Blood glucose decreased
Blood lactic acid increased
Blood potassium increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Completed suicide (act of taking one's own life)
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Loss of consciousness

60+:

Malaise (a feeling of general discomfort or uneasiness)
Substance abuse
Osteonecrosis of jaw (death of bone of jaw)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 24.00%
Pain: 3 people, 12.00%
Muscle Spasms (muscle contraction): 2 people, 8.00%
Insomnia (sleeplessness): 2 people, 8.00%
Drug Dependence: 2 people, 8.00%
Alcoholism (problems with alcohol): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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