Diamox and Cymbalta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diamox (acetazolamide) and Cymbalta (duloxetine hydrochloride). Common drug interactions include diarrhoea among females and pulmonary oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Diamox and Cymbalta. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

On Jul, 03, 2026

89 people who take Diamox and Cymbalta together, and have interactions are studied.

What are the common drug interactions of Diamox and Cymbalta, by gender? *:

female:

Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Muscle rigidity (muscle stiffness)
Muscle twitching
Alopecia (absence of hair from areas of the body)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Infusion related reaction
Neck pain
Papilloedema (optic disc swelling)

male:

Pulmonary oedema (fluid accumulation in the lungs)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Fall
Haemorrhage (bleeding)
Osteonecrosis (death of bone)
Shoulder operation
Platelet count decreased
Abasia (inability to walk)
Aggression
Anaemia (lack of blood)

What are the common drug interactions of Diamox and Cymbalta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cough
Depressed level of consciousness
Influenza
Retching (strong involuntary effort to vomit)
Vomiting
Migraine (headache)
Pyrexia (fever)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Crying
Drug hypersensitivity

30-39:

Headache (pain in head)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Nausea (feeling of having an urge to vomit)
Papilloedema (optic disc swelling)
Dizziness
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Neck pain
Tension headache
Abdominal discomfort
Abnormal dreams

40-49:

Emotional distress
Headache (pain in head)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Urinary tract infection
Anisocytosis (patient's red blood cells are of unequal size)
Blood methanol increased
Chest pain
Chronic kidney disease
Confusional state

50-59:

Bronchial obstruction (blockage of the breathing passages to the lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrospinal fluid leakage
Chest pain
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Encephalocele (hernia of the brain that is either congenital or due to trauma)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pulmonary oedema (fluid accumulation in the lungs)
Alopecia (absence of hair from areas of the body)
Arthropathy
Blood cholesterol increased
Blood pressure increased
Eye disorder
Infusion related reaction
Sleep disorder
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 23.60%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 12.36%
Migraine (headache): 11 people, 12.36%
Stress And Anxiety: 10 people, 11.24%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 10.11%
Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 8.99%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 6.74%
Pain: 6 people, 6.74%
Blood Potassium Decreased: 6 people, 6.74%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 6 people, 6.74%

* Approximation only. Some reports may have incomplete information.

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