Cymbalta and Lexiscan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cymbalta (duloxetine hydrochloride) and Lexiscan (regadenoson). Common drug interactions include blood pressure increased among females and chest pain among males.
The phase IV clinical study analyzes what interactions people have when they take Cymbalta and Lexiscan. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Cymbalta?
Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,974 Cymbalta users. Check the latest studies of Cymbalta.
What is Lexiscan?
Lexiscan has active ingredients of regadenoson. eHealthMe is studying from 4,442 Lexiscan users. Check the latest studies of Lexiscan.
28 people who take Cymbalta and Lexiscan together, and have interactions are studied.

What are the common drug interactions of Cymbalta and Lexiscan, by gender? *:
female:
- Blood pressure increased
- Abdominal pain upper
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dyspnoea (difficult or laboured respiration)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Chest pain
- Chest discomfort
- Muscle spasms (muscle contraction)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Platelet count increased
male:
- Chest pain
- Heart rate increased
- Acute respiratory failure
- Agitation (state of anxiety or nervous excitement)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Blood pressure systolic increased
- Blood thyroid stimulating hormone increased
- Bradycardia (abnormally slow heart action)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Depressed level of consciousness
What are the common drug interactions of Cymbalta and Lexiscan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal pain upper
- Blood pressure increased
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Depressed level of consciousness
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Muscular weakness (muscle weakness)
- Slow response to stimuli (slow response by nerves)
- Social avoidant behaviour (avoiding social connection a personality disorder)
- Chest discomfort
60+:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Anaphylactic reaction (serious allergic reaction)
- Back pain
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Hypoaesthesia (reduced sense of touch or sensation)
- Cardiac arrest
- Chest discomfort
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
What are the existing conditions these people have? *
- High Blood Cholesterol: 5 people, 17.86%
- Pain: 4 people, 14.29%
- High Blood Pressure: 3 people, 10.71%
- Constipation: 3 people, 10.71%
- Stress And Anxiety: 2 people, 7.14%
- Nausea (feeling of having an urge to vomit): 2 people, 7.14%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.14%
- Chest Pain: 2 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Cymbalta and Lexiscan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cymbalta and Lexiscan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cymbalta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexiscan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cymbalta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexiscan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on duloxetine hydrochloride and regadenoson (the active ingredients of Cymbalta and Lexiscan, respectively), and Cymbalta and Lexiscan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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