Cytomel and Delsym drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytomel (liothyronine sodium) and Delsym (dextromethorphan polistirex). Common drug interactions include constipation among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Cytomel and Delsym. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cytomel?

Cytomel has active ingredients of liothyronine sodium. It is often used in hypothyroidism. eHealthMe is studying from 7,595 Cytomel users. Check the latest studies of Cytomel.

What is Delsym?

Delsym has active ingredients of dextromethorphan polistirex. It is often used in cough. eHealthMe is studying from 5,033 Delsym users. Check the latest studies of Delsym.



On Jul, 06, 2026

13 people who take Cytomel and Delsym together, and have interactions are studied.

Cytomel and Delsym drug interactions.

What are the common drug interactions of Cytomel and Delsym, by gender? *:

female:

  1. Constipation
  2. Vomiting
  3. Abdominal discomfort
  4. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  5. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  6. Hunger
  7. Hypersensitivity
  8. Infection
  9. Insomnia (sleeplessness)
  10. Laryngitis (inflammation of the larynx)

male:

  1. White blood cell count decreased

What are the common drug interactions of Cytomel and Delsym, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  3. Infection
  4. Pyrexia (fever)
  5. Respiratory disorder (respiratory disease)
  6. Weight fluctuation
  7. Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

n/a

60+:

  1. Hypersensitivity
  2. Laryngitis (inflammation of the larynx)
  3. Skin wrinkling (wrinkle on skin)
  4. Tooth disorder (tooth disease)
  5. Viral upper respiratory tract infection
  6. Anaemia (lack of blood)
  7. Constipation
  8. Drug ineffective
  9. Dyspepsia (indigestion)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 69.23%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 69.23%
  3. High Blood Pressure: 4 people, 30.77%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 23.08%
  5. Depression: 1 person, 7.69%
  6. Breast Cancer: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cytomel and Delsym?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cytomel and Delsym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cytomel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Delsym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytomel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Delsym and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on liothyronine sodium and dextromethorphan polistirex (the active ingredients of Cytomel and Delsym, respectively), and Cytomel and Delsym (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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