Cytomel and Relafen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytomel (liothyronine sodium) and Relafen (nabumetone). Common drug interactions include optic neuritis among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Cytomel and Relafen. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Cytomel?

Cytomel has active ingredients of liothyronine sodium. It is often used in hypothyroidism. eHealthMe is studying from 7,595 Cytomel users. Check the latest studies of Cytomel.

What is Relafen?

Relafen has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 6,243 Relafen users. Check the latest studies of Relafen.

On Jul, 12, 2026

23 people who take Cytomel and Relafen together, and have interactions are studied.

What are the common drug interactions of Cytomel and Relafen, by gender? *:

female:

Optic neuritis (optic nerve inflammation)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Retinal disorder (disease of retina)
Retinal scar (development of scar tissue on retina)
Retinopathy (acute damage to the retina of the eye)
Scar
Vitreous disorder (eye disease)
Vitreous floaters (spots before the eyes)
Arrhythmia (irregular heartbeat)
Arthrodesis

male:

Flushing (the warm, red condition of human skin)
Muscle cramps (painful sensations caused by muscle contraction)

What are the common drug interactions of Cytomel and Relafen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Colour blindness (inability to view some colour)
Iron deficiency anaemia
Joint swelling
Metamorphopsia (a type of distorted vision in which a grid of straight lines appears wavy and parts of the grid may appear blank)
Optic neuritis (optic nerve inflammation)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Retinal disorder (disease of retina)
Scar
Sinusitis (inflammation of sinus)
Vitreous disorder (eye disease)

50-59:

Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Retinal scar (development of scar tissue on retina)
Retinopathy (acute damage to the retina of the eye)
Sinusitis (inflammation of sinus)
Tendon injury
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
Tremor (trembling or shaking movements in one or more parts of your body)
Death
Difficulty in walking
Dizziness (excl vertigo)

60+:

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Muscle cramps (painful sensations caused by muscle contraction)
Retinal scar (development of scar tissue on retina)
Retinopathy (acute damage to the retina of the eye)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 26.09%
Migraine (headache): 6 people, 26.09%
Insomnia (sleeplessness): 6 people, 26.09%
High Blood Cholesterol: 5 people, 21.74%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
Hypersensitivity: 4 people, 17.39%
Essential Tremor: 4 people, 17.39%
Asthma: 4 people, 17.39%
Gastritis (inflammation of stomach): 3 people, 13.04%
Spinal Column Stenosis (narrowing of spinal column): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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