Cytosar-u and Acyclovir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cytosar-u (cytarabine) and Acyclovir (acyclovir). Common drug interactions include bradycardia among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Cytosar-u and Acyclovir. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Cytosar-u?
Cytosar-u has active ingredients of cytarabine. eHealthMe is studying from 586 Cytosar-u users. Check the latest studies of Cytosar-u.
What is Acyclovir?
Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.
14 people who take Cytosar-u and Acyclovir together, and have interactions are studied.

What are the common drug interactions of Cytosar-U and Acyclovir, by gender? *:
female:
- Bradycardia (abnormally slow heart action)
- Blood phosphate decreased
- Cardiac failure congestive
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Gingival bleeding (bleeding gums)
- Haematemesis (vomiting of blood)
- Haemorrhage (bleeding)
- Headache (pain in head)
- Injection site pain
male:
- Diarrhoea
- Headache (pain in head)
- Joint swelling
- Mucosal inflammation (infection of mucous membrane)
- Myalgia (muscle pain)
- Pulmonary oedema (fluid accumulation in the lungs)
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abdominal pain
- Pain
What are the common drug interactions of Cytosar-U and Acyclovir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Asthenia (weakness)
- Back pain
- Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cushing's syndrome (obesity, a rounded face, increased fat)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Graft dysfunction
30-39:
- Abdominal pain
- Abdominal rigidity
- Abdominal tenderness
- Colitis (inflammation of colon)
- Diarrhoea
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Hypotension (abnormally low blood pressure)
- Intestinal perforation (complete penetration of the wall of the intestine)
- Pain
40-49:
- Agitation (state of anxiety or nervous excitement)
- Blood pressure decreased
- Blood pressure increased
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Fall
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hemiparesis (weakness on one side of the body)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
50-59:
- Diarrhoea
- Hypotension (abnormally low blood pressure)
- Insomnia (sleeplessness)
- Oropharyngeal pain
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abdominal pain
- Chills (felling of cold)
- Epididymitis (pain in the scrotum or testicle)
- Febrile neutropenia (fever with reduced white blood cells)
- Gingival bleeding (bleeding gums)
60+:
- Blood phosphate decreased
- Cardiac failure congestive
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Oxygen saturation decreased
- Pruritus (severe itching of the skin)
- Pulmonary oedema (fluid accumulation in the lungs)
- Rash erythematous (redness of the skin)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 3 people, 21.43%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 21.43%
- Pain: 2 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Cytosar-u and Acyclovir?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cytosar-u and Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cytosar-u:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cytosar-u and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on cytarabine and acyclovir (the active ingredients of Cytosar-u and Acyclovir, respectively), and Cytosar-u and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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