Cytosar-u and Adriamycin pfs drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytosar-u (cytarabine) and Adriamycin pfs (doxorubicin hydrochloride). Common drug interactions include bladder fibrosis among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Cytosar-u and Adriamycin pfs. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cytosar-u?

Cytosar-u has active ingredients of cytarabine. eHealthMe is studying from 586 Cytosar-u users. Check the latest studies of Cytosar-u.

What is Adriamycin pfs?

Adriamycin pfs has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 6,495 Adriamycin pfs users. Check the latest studies of Adriamycin pfs.



On Jul, 14, 2026

13 people who take Cytosar-u and Adriamycin pfs together, and have interactions are studied.

Cytosar-u and Adriamycin pfs drug interactions.

What are the common drug interactions of Cytosar-U and Adriamycin Pfs, by gender? *:

female:

  1. Bladder fibrosis (formation of excess fibrous connective tissue in bladder)
  2. Cerebellar ataxia (loss of coordination)
  3. Haematuria (presence of blood in urine)
  4. Urinary bladder haemorrhage (urinary bladder bleeding)
  5. Ulcer
  6. Asthenia (weakness)
  7. Diarrhoea
  8. Dizziness
  9. Electrocardiogram t wave inversion
  10. Haematocrit decreased

male:

  1. Alanine aminotransferase increased
  2. Anaemia (lack of blood)
  3. Headache (pain in head)
  4. Hodgkin's disease (cancer originating from white blood cells)
  5. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  6. Lymphadenopathy (disease or enlargement of lymph nodes)
  7. Nausea (feeling of having an urge to vomit)
  8. Night sweats (sweating in night)
  9. Oral disorder (mouth disease)
  10. Oropharyngeal pain

What are the common drug interactions of Cytosar-U and Adriamycin Pfs, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Second primary malignancy (after getting cure a cancer, a new cancer development)

10-19:

  1. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

20-29:

  1. Alanine aminotransferase increased
  2. Anaemia (lack of blood)
  3. Anxiety
  4. Aspartate aminotransferase increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Dizziness
  7. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Febrile neutropenia (fever with reduced white blood cells)

30-39:

n/a

40-49:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
  3. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

50-59:

  1. Bladder fibrosis (formation of excess fibrous connective tissue in bladder)
  2. Cerebellar ataxia (loss of coordination)
  3. Haemoglobin decreased
  4. Hypotension (abnormally low blood pressure)
  5. Inflammation
  6. Leukocytosis (increased white blood cells)
  7. Mucosal ulceration (ulcers of mucous membrane)
  8. Nausea (feeling of having an urge to vomit)
  9. Sweating increased (excess sweating)
  10. Vomiting

60+:

n/a

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 23.08%
  2. Stress And Anxiety: 2 people, 15.38%
  3. Nausea And Vomiting: 2 people, 15.38%
  4. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  5. Gastric Ph Decreased: 2 people, 15.38%
  6. Gastric Disorder (disease of stomach): 2 people, 15.38%
  7. Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 1 person, 7.69%
  8. Fungal Infection: 1 person, 7.69%
  9. Breast Cancer Female: 1 person, 7.69%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cytosar-u and Adriamycin pfs:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cytosar-u:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adriamycin pfs:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytosar-u and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adriamycin pfs and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cytarabine and doxorubicin hydrochloride (the active ingredients of Cytosar-u and Adriamycin pfs, respectively), and Cytosar-u and Adriamycin pfs (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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