Cytotec and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytotec (misoprostol) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include cardiac failure congestive among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Cytotec and Centrum. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cytotec?

Cytotec has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 5,812 Cytotec users. Check the latest studies of Cytotec.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.



On Jul, 11, 2026

18 people who take Cytotec and Centrum together, and have interactions are studied.

Cytotec and Centrum drug interactions.

What are the common drug interactions of Cytotec and Centrum, by gender? *:

female:

  1. Cardiac failure congestive
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Long qt syndrome (disorder of the heart's electrical system)
  4. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  5. Diarrhoea
  6. Gastritis (inflammation of stomach)
  7. Blood pressure increased
  8. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Drug ineffective
  2. Pneumonia
  3. Hypotension (abnormally low blood pressure)
  4. Strangulated hernia (a dangerous condition in which the blood supply to the hernia is cut off)
  5. Sutre rupture
  6. Abdominal hernia
  7. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  8. Cough
  9. Insomnia (sleeplessness)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Cytotec and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)

50-59:

n/a

60+:

  1. Cardiac failure congestive
  2. Drug ineffective
  3. Blood pressure increased
  4. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Pneumonia
  7. Hypotension (abnormally low blood pressure)
  8. Oxygen saturation decreased
  9. Pain
  10. Abdominal hernia

What are the existing conditions these people have? *

  1. Dementia (madness): 4 people, 22.22%
  2. Type 2 Diabetes: 1 person, 5.56%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.56%
  5. Pain: 1 person, 5.56%
  6. Nausea And Vomiting: 1 person, 5.56%
  7. Nausea (feeling of having an urge to vomit): 1 person, 5.56%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.56%
  9. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 5.56%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Cytotec and Centrum?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cytotec and Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cytotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on misoprostol and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Cytotec and Centrum, respectively), and Cytotec and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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