Dacogen and Neulasta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dacogen (decitabine) and Neulasta (pegfilgrastim). Common drug interactions include pyrexia among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Dacogen and Neulasta. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Dacogen?

Dacogen has active ingredients of decitabine. eHealthMe is studying from 1,541 Dacogen users. Check the latest studies of Dacogen.

What is Neulasta?

Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.



On Jul, 09, 2026

41 people who take Dacogen and Neulasta together, and have interactions are studied.

Dacogen and Neulasta drug interactions.

What are the common drug interactions of Dacogen and Neulasta, by gender? *:

female:

  1. Pyrexia (fever)
  2. Drug ineffective
  3. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  4. White blood cell count decreased
  5. Death
  6. Fungal infection
  7. Pain in extremity
  8. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  9. Pneumonia
  10. Anaemia (lack of blood)

male:

  1. White blood cell count decreased
  2. Death
  3. Platelet count decreased
  4. Pyrexia (fever)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. White blood cell count increased
  7. Device occlusion
  8. Pain in extremity
  9. Anaemia (lack of blood)
  10. Aphagia (inability or refusal to swallow)

What are the common drug interactions of Dacogen and Neulasta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Death
  2. Pyrexia (fever)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Device occlusion
  5. Aphagia (inability or refusal to swallow)
  6. Application site discomfort
  7. Asthenia (weakness)
  8. Blast cell crisis
  9. Blood lactate dehydrogenase increased
  10. Bone marrow failure

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 23 people, 56.10%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 10 people, 24.39%
  3. Nausea (feeling of having an urge to vomit): 7 people, 17.07%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 17.07%
  5. Essential Thrombocythaemia (chronic blood cancer): 6 people, 14.63%
  6. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 7.32%
  7. Neoplasm Malignant (cancer tumour): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Dacogen and Neulasta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dacogen and Neulasta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dacogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Neulasta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dacogen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neulasta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on decitabine and pegfilgrastim (the active ingredients of Dacogen and Neulasta, respectively), and Dacogen and Neulasta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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