Dactinomycin and Heparin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dactinomycin (dactinomycin) and Heparin (heparin sodium). Common drug interactions include drug toxicity among females and compartment syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Dactinomycin and Heparin. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Dactinomycin?

Dactinomycin has active ingredients of dactinomycin. eHealthMe is studying from 2,577 Dactinomycin users. Check the latest studies of Dactinomycin.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

On Jul, 29, 2026

47 people who take Dactinomycin and Heparin together, and have interactions are studied.

Dactinomycin and Heparin drug interactions.

What are the common drug interactions of Dactinomycin and Heparin, by gender? *:

female:

Drug toxicity
Device failure
Headache (pain in head)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)

male:

Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Death
Drug toxicity
Hospitalisation
Pyrexia (fever)
Vomiting

What are the common drug interactions of Dactinomycin and Heparin, by age (0-1 to 60+)? *:

0-1:

Ascites (accumulation of fluid in the abdominal cavity)
Coagulopathy (blood's ability to clot is impaired)
Death
Hospitalisation
Hyperbilirubinaemia (excess of bilirubin in the blood)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Transaminases increased
Venoocclusive disease (small veins in the liver are obstructed)

2-9:

Pleural effusion (water on the lungs)
Respiratory disorder (respiratory disease)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Coagulopathy (blood's ability to clot is impaired)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Transaminases increased
Venoocclusive disease (small veins in the liver are obstructed)

10-19:

Abdominal pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Myalgia (muscle pain)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)
Gait disturbance
Motor neurone disease (a rare condition where parts of the nervous system become damaged, causing progressive weakness)

20-29:

Device failure
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Bone marrow failure

30-39:

Ototoxicity (damage to the ear)
Thrombocytopenia (decrease of platelets in blood)
Tinnitus (a ringing in the ears)

40-49:

n/a

50-59:

Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Drug toxicity

60+:

Cellulitis (infection under the skin)
Drug toxicity
Medical device complication
Systemic leakage (a condition in which fluid and proteins leak out of tiny blood vessels and flow into surrounding tissues)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Urinary tract infection
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

What are the existing conditions these people have? *

Malignant Melanoma Stage Iii (cancer has spread to one or more lymph nodes): 12 people, 25.53%
Skin Cancer: 6 people, 12.77%
Malignant Soft Tissue Neoplasm (cancer tumour of soft tissue): 4 people, 8.51%
Gestational Trophoblastic Tumor: 4 people, 8.51%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 3 people, 6.38%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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