Dalmane and Aldactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dalmane (flurazepam hydrochloride) and Aldactone (spironolactone). Common drug interactions include fatigue among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Dalmane and Aldactone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Dalmane?

Dalmane has active ingredients of flurazepam hydrochloride. It is often used in insomnia. eHealthMe is studying from 1,269 Dalmane users. Check the latest studies of Dalmane.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

On Aug, 01, 2026

12 people who take Dalmane and Aldactone together, and have interactions are studied.

Dalmane and Aldactone drug interactions.

What are the common drug interactions of Dalmane and Aldactone, by gender? *:

female:

Fatigue (feeling of tiredness)
Headache (pain in head)
Myalgia (muscle pain)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arteriosclerosis (thickening and hardening of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure decreased

male:

Abnormal behaviour
Aggression
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Judgement impaired
Mania (a state of abnormally elevated or irritable mood)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychotic disorder
Renal impairment (severely reduced kidney function)
Blood creatinine increased
Cardiac failure

What are the common drug interactions of Dalmane and Aldactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arteriosclerosis (thickening and hardening of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood bilirubin increased
Blood creatinine increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fibromyalgia (a long-term condition which causes pain all over the body)
Haemoglobin decreased
Hyperbilirubinaemia (excess of bilirubin in the blood)

50-59:

Fatigue (feeling of tiredness)
Headache (pain in head)
Myalgia (muscle pain)

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Back pain
Headache (pain in head)
Inflammation
Muscle spasms (muscle contraction)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Myalgia (muscle pain)
Neck pain
Rectal haemorrhage (bleeding from anus)
Respiratory tract infection

What are the existing conditions these people have? *

Parkinson's Disease: 2 people, 16.67%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 8.33%
Sleep Disorder: 1 person, 8.33%
Respiratory Tract Infection: 1 person, 8.33%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
Muscle Spasms (muscle contraction): 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Gout (uric acid crystals building up in the body): 1 person, 8.33%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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