Dalmane and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dalmane (flurazepam hydrochloride) and Premarin (estrogens, conjugated). Common drug interactions include chest pain among females and angina unstable among males.

The phase IV clinical study analyzes what interactions people have when they take Dalmane and Premarin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Dalmane?

Dalmane has active ingredients of flurazepam hydrochloride. It is often used in insomnia. eHealthMe is studying from 1,269 Dalmane users. Check the latest studies of Dalmane.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 14, 2026

53 people who take Dalmane and Premarin together, and have interactions are studied.

What are the common drug interactions of Dalmane and Premarin, by gender? *:

female:

Chest pain
Bone disorder
Cardiomyopathy (weakening of the heart muscle)
Dizziness
Road traffic accident
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Osteonecrosis of jaw (death of bone of jaw)
Pyrexia (fever)

male:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Balance disorder
Biliary colic
Bone disorder
Bone swelling
Breath sounds absent
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the common drug interactions of Dalmane and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess (pus)
Anaemia of chronic disease
Anxiety
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood glucose increased
Blood pressure fluctuation

20-29:

Abscess (pus)
Anaemia of chronic disease
Anxiety
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood urea increased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

30-39:

n/a

40-49:

Acute hepatic failure
Alanine aminotransferase increased
Amphetamines positive
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Aspartate aminotransferase increased
Blood creatinine increased
Chest pain

50-59:

Cardiomyopathy (weakening of the heart muscle)
Depression
Dizziness
Electrocardiogram qt prolonged
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Impaired healing
Injury
Laryngeal oedema (swelling of larynx)
Loss of consciousness
Muscle spasms (muscle contraction)

60+:

Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Dizziness
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypotension (abnormally low blood pressure)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Road traffic accident

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 16.98%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 15.09%
High Blood Cholesterol: 8 people, 15.09%
Breast Cancer Metastatic: 8 people, 15.09%
Pain: 4 people, 7.55%
Bipolar Disorder (mood disorder): 4 people, 7.55%
Tonsil Cancer: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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