Dantrium and Singulair drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dantrium (dantrolene sodium) and Singulair (montelukast sodium). Common drug interactions include diarrhoea among females and hyponatraemia among males.
The phase IV clinical study analyzes what interactions people have when they take Dantrium and Singulair. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Dantrium?
Dantrium has active ingredients of dantrolene sodium. eHealthMe is studying from 1,408 Dantrium users. Check the latest studies of Dantrium.
What is Singulair?
Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.
21 people who take Dantrium and Singulair together, and have interactions are studied.

What are the common drug interactions of Dantrium and Singulair, by gender? *:
female:
- Diarrhoea
- Eye infection
- Pneumonia
- Vomiting
- Abasia (inability to walk)
- Blood pressure increased
- Crying
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspepsia (indigestion)
male:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Inappropriate antidiuretic hormone secretion
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Gastritis (inflammation of stomach)
- Cough
- Hepatitis (inflammation of the liver)
- Hepatotoxicity (chemical-driven liver damage)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
What are the common drug interactions of Dantrium and Singulair, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Gastritis (inflammation of stomach)
10-19:
n/a
20-29:
n/a
30-39:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Inappropriate antidiuretic hormone secretion
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
40-49:
- Cough
- Hepatitis (inflammation of the liver)
50-59:
- Urinary tract infection
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hepatotoxicity (chemical-driven liver damage)
- Kidney infection
- Loss of control of legs
- Muscular weakness (muscle weakness)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Pneumonia
- Sinusitis (inflammation of sinus)
60+:
- Pruritus (severe itching of the skin)
What are the existing conditions these people have? *
- Behcet's Syndrome (involves inflammation of the blood vessels): 9 people, 42.86%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 7 people, 33.33%
- Infantile Spasms: 2 people, 9.52%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Dantrium and Singulair?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dantrium and Singulair:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dantrium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Singulair:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dantrium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Singulair and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on dantrolene sodium and montelukast sodium (the active ingredients of Dantrium and Singulair, respectively), and Dantrium and Singulair (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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