Dapsone and Klor-con drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dapsone (dapsone) and Klor-con (potassium chloride). Common drug interactions include deep vein thrombosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Dapsone and Klor-con. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Klor-con?

Klor-con has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 27,547 Klor-con users. Check the latest studies of Klor-con.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

83 people who take Dapsone and Klor-con together, and have interactions are studied.

What are the common drug interactions of Dapsone and Klor-Con, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea exertional (breathlessness or shortness of breath)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Febrile neutropenia (fever with reduced white blood cells)
Fluid retention (an abnormal accumulation of fluid in the blood)
Joint effusion (presence of extra fluid in joint covering)
Oedema (fluid collection in tissue)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Oxygen saturation decreased
Platelet count decreased

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Bone metabolism disorder
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death

What are the common drug interactions of Dapsone and Klor-Con, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia (lack of blood)
Renal failure acute (rapid kidney dysfunction)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Pneumonia
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased

30-39:

n/a

40-49:

Diarrhoea
Vomiting
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dehydration (dryness resulting from the removal of water)
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Pain
Pancreatitis (inflammation of pancreas)
Anaemia (lack of blood)

50-59:

Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Rash
Renal tubular necrosis (death of kidney tubules)
Respiratory syncytial virus infection (viral disease of respiratory system)
Rib fracture
Septic shock (shock due to blood infection)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

60+:

Diarrhoea
Duodenitis (inflammation of the duodenum)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood potassium decreased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Disturbance in attention
Drug ineffective
Feeling jittery
Full blood count decreased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 28 people, 33.73%
Hiv Infection: 21 people, 25.30%
Nausea (feeling of having an urge to vomit): 8 people, 9.64%
Pain: 5 people, 6.02%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.02%
Depression: 5 people, 6.02%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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