Dapsone and Peridex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dapsone (dapsone) and Peridex (chlorhexidine gluconate). Common drug interactions include vomiting among females and ileitis among males.

The phase IV clinical study analyzes what interactions people have when they take Dapsone and Peridex. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

On Aug, 05, 2026

34 people who take Dapsone and Peridex together, and have interactions are studied.

What are the common drug interactions of Dapsone and Peridex, by gender? *:

female:

Vomiting
Adverse drug reaction
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blepharitis (chronic inflammation of the eyelid)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiomyopathy (weakening of the heart muscle)
Cataract (clouding of the lens inside the eye)
Cerebral oedema (swelling of brain)

male:

Ileitis (inflammation of the ileum)
Cholecystitis (infection of gallbladder)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain
Cough
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mycobacterium avium complex infection
Occult blood positive
Pneumonia

What are the common drug interactions of Dapsone and Peridex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cough
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Incoherent (talking in a confused and unclear way)
Somnolence (a state of near-sleep, a strong desire for sleep)
Superior vena caval obstruction (obstruction of blood flow through the superior vena cava)
Thrombosis (formation of a blood clot inside a blood vessel)

10-19:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Malaise (a feeling of general discomfort or uneasiness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Blood creatinine increased
Chorea (abnormal involuntary movement disorder)
Dyskinesia (abnormality or impairment of voluntary movement)
Haemoglobin decreased
Hypoglycaemia (deficiency of glucose in the bloodstream)
Platelet count decreased
Pyrexia (fever)

20-29:

n/a

30-39:

Lymphoma (cancer that begins in immune system cells)
Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue)
Metastases to spine (cancer spreads to spine)
Oesophageal candidiasis (fungal infection of oesophagus)
Oesophageal dilatation (enlarged oesophagus)
Osteonecrosis of jaw (death of bone of jaw)
Osteoporosis (bones weak and more likely to break)
Pain
Papule
Pathological fracture (broken bone caused by disease)

40-49:

Ileitis (inflammation of the ileum)
Cholecystitis (infection of gallbladder)
Osteonecrosis (death of bone)
Anaemia (lack of blood)
Diarrhoea
Immune reconstitution syndrome (immune recovery syndrome)
Mycobacterium avium complex immune restoration disease
Nausea (feeling of having an urge to vomit)
Abdominal pain
Mycobacterium avium complex infection

50-59:

Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Foot fracture
Gastric ulcer (stomach ulcer)
General physical health deterioration (weak health status)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Influenza
Lung neoplasm (tumour of lung)
Lymphoma (cancer that begins in immune system cells)

60+:

Pyrexia (fever)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Richter's syndrome (hairy cell cancer changes in fast growing b cell cancer tumour)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 4 people, 11.76%
Multiple Myeloma (cancer of the plasma cells): 4 people, 11.76%
Oropharyngeal Pain: 3 people, 8.82%
Neuropathy Peripheral (surface nerve damage): 3 people, 8.82%
Hiv Infection: 3 people, 8.82%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 8.82%
Pain: 2 people, 5.88%
Hereditary Haemochromatosis (hereditary condition -excessive amounts of iron accumulate in the body tissues): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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