Dapsone and Vagifem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dapsone (dapsone) and Vagifem (estradiol). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Dapsone and Vagifem. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Vagifem?

Vagifem has active ingredients of estradiol. It is often used in vulvovaginal dryness. eHealthMe is studying from 6,263 Vagifem users. Check the latest studies of Vagifem.



On Jul, 13, 2026

26 people who take Dapsone and Vagifem together, and have interactions are studied.

Dapsone and Vagifem drug interactions.

What are the common drug interactions of Dapsone and Vagifem, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Pancreatitis (inflammation of pancreas)
  3. Vasculitis gastrointestinal (inflammation of the blood vessel wall involving the gastrointestinal)
  4. Anaemia (lack of blood)
  5. Arthralgia (joint pain)
  6. Bone pain
  7. Constipation
  8. Cough
  9. Dry mouth
  10. Dyspnoea (difficult or laboured respiration)

male:

n/a

What are the common drug interactions of Dapsone and Vagifem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Dizziness

60+:

  1. Blood disorder
  2. Disease progression
  3. Fatigue (feeling of tiredness)
  4. Haematocrit decreased
  5. Haemoglobin decreased
  6. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  7. Infusion site bruising
  8. Infusion site pain
  9. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  10. Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 7 people, 26.92%
  2. Multiple Myeloma (cancer of the plasma cells): 5 people, 19.23%
  3. Nausea (feeling of having an urge to vomit): 3 people, 11.54%
  4. Quit Smoking: 2 people, 7.69%
  5. Ocular Pemphigoid (inflammatory autoimmune disorder characterized by blistering lesions that affect mucous membrane covering of eye): 2 people, 7.69%
  6. Nausea And Vomiting: 2 people, 7.69%
  7. Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 2 people, 7.69%
  8. Interstitial Lung Disease: 2 people, 7.69%
  9. Insomnia (sleeplessness): 2 people, 7.69%
  10. Incontinence (lack of moderation or self-control): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Dapsone and Vagifem?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dapsone and Vagifem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dapsone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vagifem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dapsone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vagifem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dapsone and estradiol (the active ingredients of Dapsone and Vagifem, respectively), and Dapsone and Vagifem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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