Daptomycin and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Erythromycin (erythromycin). Common drug interactions include hyperventilation among females and pathogen resistance among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Erythromycin. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

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On Aug, 20, 2026

42 people who take Daptomycin and Erythromycin together, and have interactions are studied.

Daptomycin and Erythromycin drug interactions.

What are the common drug interactions of Daptomycin and Erythromycin, by gender? *:

female:

Hyperventilation
Leukopenia (less number of white blood cells in blood)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)
Renal impairment (severely reduced kidney function)
Sensory disturbance (sense disturbance)
Staphylococcus test positive
White blood cell count decreased

male:

Pathogen resistance
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Herpes simplex ophthalmic (eye infection is caused by a type of herpes simplex virus)
Hypotension (abnormally low blood pressure)
Pneumonia
Pneumonia fungal
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Unresponsive to stimuli
Abscess limb (limb infection)

What are the common drug interactions of Daptomycin and Erythromycin, by age (0-1 to 60+)? *:

0-1:

Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)

2-9:

n/a

10-19:

Myositis (inflammation of the muscles)
Cerebral haemorrhage (bleeding within the brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Pneumonia viral
Pulmonary sepsis (pus in lungs)

20-29:

Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Renal failure acute (rapid kidney dysfunction)
Respiratory distress (difficulty in breathing)
Acute respiratory failure
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Herpes simplex ophthalmic (eye infection is caused by a type of herpes simplex virus)
Pneumonia
Pneumonia fungal
Pneumonia viral
Pulmonary haemorrhage (acute bleeding from the lung)

30-39:

Hypokalaemia (low potassium)
Pancreatitis acute (sudden inflammation of pancreas)
Urinary tract infection
Venous thrombosis limb (blood clot that forms in a vein in the limb)
Coma (state of unconsciousness lasting more than six hours)
Lactic acidosis (low ph in body tissues)

40-49:

Abscess limb (limb infection)
Arthralgia (joint pain)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Drug intolerance (drug sensitivity)
Hypervolaemia (abnormally increased volume of blood)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Intestinal pseudo-obstruction (syndrome caused by severe impairment in the ability of the intestines to push food through)
Joint effusion (presence of extra fluid in joint covering)
Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

50-59:

Angioedema (rapid swelling of the dermis)
Bone pain
Fatigue (feeling of tiredness)
Oral pain
Pruritus (severe itching of the skin)
Rash
Swollen tongue (swelling of tongue)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anaphylactic reaction (serious allergic reaction)
Drug ineffective

60+:

Pathogen resistance
Hypotension (abnormally low blood pressure)
Hyperventilation
Jaundice cholestatic
Lactic acidosis (low ph in body tissues)
Post transplant lymphoproliferative disorder
Staphylococcus test positive
White blood cell count decreased
White blood cell count increased
Acute lung injury

What are the existing conditions these people have? *

Osteomyelitis (infection of bone): 10 people, 23.81%
Diarrhea: 6 people, 14.29%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 14.29%
Vitamin A Deficiency: 5 people, 11.90%
Depression: 5 people, 11.90%
Device Related Infection: 5 people, 11.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.90%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 11.90%
Hypoglycemia (low blood sugar): 5 people, 11.90%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 5 people, 11.90%

* Approximation only. Some reports may have incomplete information.

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