Daptomycin and Insulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Insulin (insulin pork). Common drug interactions include bacteraemia among females and blood creatine phosphokinase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Insulin. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.



On Jul, 19, 2026

75 people who take Daptomycin and Insulin together, and have interactions are studied.

Daptomycin and Insulin drug interactions.

What are the common drug interactions of Daptomycin and Insulin, by gender? *:

female:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Cellulitis (infection under the skin)
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Death
  5. Disease progression
  6. Drug resistance (reduction in effectiveness of a drug)
  7. Ear disorder
  8. Generalised oedema (swelling all over the body)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Hypoaesthesia facial (reduced sense of touch or sensation on face)

male:

  1. Blood creatine phosphokinase increased
  2. Pyrexia (fever)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Arthralgia (joint pain)
  5. Hypotension (abnormally low blood pressure)
  6. Respiratory distress (difficulty in breathing)
  7. Septic shock (shock due to blood infection)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Colitis (inflammation of colon)
  10. Eosinophilic pneumonia (eosinophil accumulates in the lung)

What are the common drug interactions of Daptomycin and Insulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pyrexia (fever)
  2. Septic shock (shock due to blood infection)
  3. Pneumonia

30-39:

  1. Acute interstitial pneumonitis (acute revere lung disease)
  2. Arthralgia (joint pain)
  3. Blood creatine phosphokinase increased
  4. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  5. Hypoxia (low oxygen in tissues)
  6. Joint swelling
  7. Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
  8. Pneumonitis chemical (inflammation of the lung caused by aspirating or inhaling irritants)
  9. Pyrexia (fever)
  10. Respiratory distress (difficulty in breathing)

40-49:

  1. Asthma
  2. Ear disorder
  3. Generalised oedema (swelling all over the body)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Hypoaesthesia facial (reduced sense of touch or sensation on face)
  6. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  7. Ill-defined disorder
  8. Injection site extravasation (flow of (blood or lymph) from injection site)
  9. Injection site swelling
  10. Mesenteric vein thrombosis (blood clot in mesenteric vein)

50-59:

  1. Renal failure (kidney dysfunction)
  2. Respiratory disorder (respiratory disease)
  3. Sputum culture positive
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. International normalised ratio increased
  6. Diarrhoea
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Colitis (inflammation of colon)
  9. Intestinal perforation (complete penetration of the wall of the intestine)
  10. Pulmonary sepsis (pus in lungs)

60+:

  1. Rash
  2. Renal impairment (severely reduced kidney function)
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Hypoxia (low oxygen in tissues)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Hypotension (abnormally low blood pressure)
  7. Acute myocardial infarction (acute heart attack)
  8. Hydronephrosis (water inside the kidney)
  9. Hyperoxaluria (excessive urinary excretion of oxalate)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

  1. Sepsis (a severe blood infection that can lead to organ failure and death): 14 people, 18.67%
  2. Pain: 11 people, 14.67%
  3. High Blood Pressure: 10 people, 13.33%
  4. Anaemia (lack of blood): 8 people, 10.67%
  5. Nausea (feeling of having an urge to vomit): 7 people, 9.33%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 8.00%
  7. Pneumonia: 6 people, 8.00%
  8. Stress And Anxiety: 6 people, 8.00%
  9. Depression: 5 people, 6.67%
  10. Constipation: 5 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daptomycin and Insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Insulin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and insulin pork (the active ingredients of Daptomycin and Insulin, respectively), and Daptomycin and Insulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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